Literature DB >> 15234780

In vivo and in vitro effect of latex of Calotropis procera on gastrointestinal smooth muscles.

V L Kumar1, Y M Shivkar.   

Abstract

The present study was carried out to evaluate the effect of dry latex (DL) of Calotropis procera on smooth muscles of gastrointestinal tract. Oral administration of DL to rats (50-1000 mg/kg) produced a dose-dependent decrease in intestinal transit along with a decrease in intestinal content as compared to control group. At lower doses DL produced dose-dependent contractions of gastrointestinal smooth muscles in vitro (rabbit ileum and fundus of rat stomach) that was followed by desensitization at higher doses.

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Year:  2004        PMID： 15234780     DOI： 10.1016/j.jep.2004.04.013

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  2 in total

1.  Antibacterial and antispasmodic activities of a dichloromethane fraction of an ethanol extract of stem bark of Piliostigma reticulatum.

Authors:  Benoit Banga N'Guessan; Kassim Dosso; Boua Narcisse Gnangoran; Patrick Amoateng; Isaac Julius Asiedu-Gyekye; Angoue Paul Yapo
Journal:  J Pharm Bioallied Sci       Date:  2015 Apr-Jun

2.  Potential Efficacy of β-Amyrin Targeting Mycobacterial Universal Stress Protein by In Vitro and In Silico Approach.

Authors:  Md Amjad Beg; Obaid Afzal; Md Sayeed Akhtar; Abdulmalik S A Altamimi; Afzal Hussain; Md Ali Imam; Mohammad Naiyaz Ahmad; Sidharth Chopra; Fareeda Athar
Journal:  Molecules       Date:  2022-07-18       Impact factor: 4.927
  2 in total

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