Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Secondary ion images of the developing rat brain.

Literature DB >> 15234370

Secondary ion images of the developing rat brain.

Peter J Todd¹, John M McMahon, Carl A McCandlish.

Abstract

Secondary ion images were obtained from sections of rat brain over a 21 day postnatal period, using the intensity of m/z 184, phosphocholine. When compared with corresponding optical images of similar, but stained sections from the same animal, the secondary ion images appear to reflect less developed brains. During development, myelination occurs after axon extension. Apparently, myelination obscures the source of secondary m/z 184, phosphatidylcholine, from the analyzing ion probe; absenting myelination, secondary ion images show no physiological features.

Entities: Chemical Species

Mesh：

Substances：
Phosphorylcholine

Year: 2004 PMID： 15234370 DOI： 10.1016/j.jasms.2004.04.029

Source DB: PubMed Journal: J Am Soc Mass Spectrom ISSN： 1044-0305 Impact factor: 3.109

14 in total

1. Secondary ion images of the rodent brain.

Authors: C A McCandlish; J M McMahon; P J Todd
Journal: J Am Soc Mass Spectrom Date: 2000-03 Impact factor: 3.109

2. Imaging with mass spectrometry.

Authors: M L Pacholski; N Winograd
Journal: Chem Rev Date: 1999-10-13 Impact factor: 60.622

3. A C60 primary ion beam system for time of flight secondary ion mass spectrometry: its development and secondary ion yield characteristics.

Authors: Daniel Weibel; Steve Wong; Nicholas Lockyer; Paul Blenkinsopp; Rowland Hill; John C Vickerman
Journal: Anal Chem Date: 2003-04-01 Impact factor: 6.986

4. A wide-angle secondary ion probe for organic ion imaging.

Authors: C C Grimm; R T Short; P J Todd
Journal: J Am Soc Mass Spectrom Date: 1991-09 Impact factor: 3.109

5. Organic ion imaging beyond the limit of static secondary ion mass spectrometry.

Authors: J M McMahon; N N Dookeran; P J Todd
Journal: J Am Soc Mass Spectrom Date: 1995-11 Impact factor: 3.109

6. Identification and mapping of phosphocholine in animal tissue by static secondary ion mass spectrometry and tandem mass spectrometry.

Authors: J M McMahon; R T Short; C A McCandlish; J T Brenna; P J Todd
Journal: Rapid Commun Mass Spectrom Date: 1996 Impact factor: 2.419

7. Regional membrane phospholipid alterations in Alzheimer's disease.

Authors: M R Prasad; M A Lovell; M Yatin; H Dhillon; W R Markesbery
Journal: Neurochem Res Date: 1998-01 Impact factor: 3.996

8. The relationships between interphase Schwann cells and axons before myelination: a quantitative electron microscopic study.

Authors: H D Webster; R Martin; M F O'Connell
Journal: Dev Biol Date: 1973-06 Impact factor: 3.582

Secondary ion images of the developing rat brain.

1. Secondary ion images of the rodent brain.

2. Imaging with mass spectrometry.

3. A C60 primary ion beam system for time of flight secondary ion mass spectrometry: its development and secondary ion yield characteristics.

4. A wide-angle secondary ion probe for organic ion imaging.

5. Organic ion imaging beyond the limit of static secondary ion mass spectrometry.

6. Identification and mapping of phosphocholine in animal tissue by static secondary ion mass spectrometry and tandem mass spectrometry.

7. Regional membrane phospholipid alterations in Alzheimer's disease.

8. The relationships between interphase Schwann cells and axons before myelination: a quantitative electron microscopic study.

9. The molecules of the immune system.

10. The intrinsic fluorescence of isolated central-nervous-system myelin-sheath preparations.

Review 1. Mass spectrometric imaging for biomedical tissue analysis.

Review 2. Imaging mass spectrometry in neuroscience.

3. Three-dimensional visualization of protein expression in mouse brain structures using imaging mass spectrometry.

4. SIMS and MALDI MS imaging of the spinal cord.