Literature DB >> 15233860

Nanosuspensions: a promising drug delivery strategy.

V B Patravale1, Abhijit A Date, R M Kulkarni.   

Abstract

Nanosuspensions have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. Techniques such as media milling and high-pressure homogenization have been used commercially for producing nanosuspensions. Recently, the engineering of nanosuspensions employing emulsions and microemulsions as templates has been addressed in the literature. The unique features of nanosuspensions have enabled their use in various dosage forms, including specialized delivery systems such as mucoadhesive hydrogels. Rapid strides have been made in the delivery of nanosuspensions by parenteral, peroral, ocular and pulmonary routes. Currently, efforts are being directed to extending their applications in site-specific drug delivery.

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Year:  2004        PMID: 15233860     DOI: 10.1211/0022357023691

Source DB:  PubMed          Journal:  J Pharm Pharmacol        ISSN: 0022-3573            Impact factor:   3.765


  121 in total

1.  A modified approach to predict dissolution and absorption of polydisperse powders.

Authors:  John C Butcher; Sanjay Garg; Dawoomi Kim; Puneet Sharma
Journal:  Pharm Res       Date:  2008-06-04       Impact factor: 4.200

2.  Downscaling drug nanosuspension production: processing aspects and physicochemical characterization.

Authors:  Bernard Van Eerdenbrugh; Bernard Stuyven; Ludo Froyen; Jan Van Humbeeck; Johan A Martens; Patrick Augustijns; Guy Van den Mooter
Journal:  AAPS PharmSciTech       Date:  2009-01-16       Impact factor: 3.246

Review 3.  A review of nanotechnological approaches for the prophylaxis of HIV/AIDS.

Authors:  Abhijit A Date; Christopher J Destache
Journal:  Biomaterials       Date:  2013-05-28       Impact factor: 12.479

4.  Preparation and in-vitro/in-vivo characterization of trans-resveratrol nanocrystals for oral administration.

Authors:  Sandeep K Singh; Vishal Makadia; Shweta Sharma; Mamunur Rashid; Sudhir Shahi; Prabhat R Mishra; Mohammed Wahajuddin; Jiaur R Gayen
Journal:  Drug Deliv Transl Res       Date:  2017-06       Impact factor: 4.617

5.  Evaluation of tadalafil nanosuspensions and their PEG solid dispersion matrices for enhancing its dissolution properties.

Authors:  Wasfy M Obeidat; Al-Sayed A Sallam
Journal:  AAPS PharmSciTech       Date:  2014-01-09       Impact factor: 3.246

6.  Nitrendipine nanocrystals: its preparation, characterization, and in vitro-in vivo evaluation.

Authors:  Peng Quan; Dengning Xia; Hongze Piao; Hongyu Piao; Kai Shi; Yinnong Jia; Fude Cui
Journal:  AAPS PharmSciTech       Date:  2011-09-03       Impact factor: 3.246

7.  Particle Surface Roughness Improves Colloidal Stability of Pressurized Pharmaceutical Suspensions.

Authors:  Hui Wang; David S Nobes; Reinhard Vehring
Journal:  Pharm Res       Date:  2019-01-30       Impact factor: 4.200

8.  The use of artificial neural networks for optimizing polydispersity index (PDI) in nanoprecipitation process of acetaminophen in microfluidic devices.

Authors:  Mahdi Aghajani; Ahmad Reza Shahverdi; Amir Amani
Journal:  AAPS PharmSciTech       Date:  2012-09-21       Impact factor: 3.246

9.  Nanosuspension based in situ gelling nasal spray of carvedilol: development, in vitro and in vivo characterization.

Authors:  Nilesh S Saindane; Kunal P Pagar; Pradeep R Vavia
Journal:  AAPS PharmSciTech       Date:  2012-12-20       Impact factor: 3.246

Review 10.  Nanomedicines in renal transplant rejection--focus on sirolimus.

Authors:  Li-Jiuan Shen; Fe-Lin Lin Wu
Journal:  Int J Nanomedicine       Date:  2007
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