Literature DB >> 15230615

Kowalski ester homologation. application to the synthesis of beta-amino esters.

Diane Gray1, Carmen Concellón, Timothy Gallagher.   

Abstract

The Kowalski ester homologation protocol has been applied to a representative range of alpha-amino esters to provide beta-amino esters with excellent levels of enantio- and diastereocontrol. A key feature of this chemistry is the nature of the N-protecting group that is employed.

Entities:  

Year:  2004        PMID: 15230615     DOI: 10.1021/jo049562h

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  2 in total

1.  Homologation of α-aryl amino acids through quinone-catalyzed decarboxylation/Mukaiyama-Mannich addition.

Authors:  Benjamin J Haugeberg; Johnny H Phan; Xinyun Liu; Thomas J O'Connor; Michael D Clift
Journal:  Chem Commun (Camb)       Date:  2017-03-09       Impact factor: 6.222

2.  Three-component synthesis of polysubstituted homoproline analogs.

Authors:  Konstantin V Kudryavtsev; Veronika V Irkha
Journal:  Molecules       Date:  2005-08-31       Impact factor: 4.411

  2 in total

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