Synthesis of 1,2-diamino-1,2-dideoxy-myo- inositol-derived ligands for the investigation of metal complex reactivity.

A method for the synthesis of chiral 1,2-diamino-1,2-dideoxy-myo-inositol-based bis-pyridyl ligands 3a and 3b from the corresponding myo-inositol precursor is described. These highly functionalized inosamine-bis-pyridyl ligands are expected to provide a useful platform for exploring the relationship between chiral ligand structure and enantioselective olefin oxidation catalyzed by their metal complexes.