Literature DB >> 1522894

Reagents for the site-specific cleavage of megabase DNA.

P B Dervan1.   

Abstract

The physical mapping of chromosomes will be facilitated by methods of breaking large DNA into manageable fragments, or cutting uniquely at genetic markers of interest. Key issues in the design of sequence-specific DNA cleaving reagents are the specificity of binding, the number of different sequences that can be targeted and the cleavage yield.

Mesh：

Substances：

Year:  1992        PMID： 1522894     DOI： 10.1038/359087a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  5 in total

1.  Efficient new ribozyme mimics: direct mapping of molecular design principles from small molecules to macromolecular, biomimetic catalysts.

Authors:  W C Putnam; A T Daniher; B N Trawick; J K Bashkin
Journal:  Nucleic Acids Res       Date:  2001-05-15       Impact factor: 16.971

2.  Cleavage of double-stranded DNA by 'metalloporphyrin-linker-oligonucleotide' molecules: influence of the linker.

Authors:  P Bigey; G Pratviel; B Meunier
Journal:  Nucleic Acids Res       Date:  1995-10-11       Impact factor: 16.971

3.  Investigation and improvement of DNA cleavage models of polyamide + Cu(II) nuclease + OOH- ligands bound to DNA.

Authors:  Hongwei Yue; Yanyan Zhu; Yan Wang; Guangju Chen
Journal:  BMC Struct Biol       Date:  2010-10-17

Review 4.  Restriction endonucleases: classification, properties, and applications.

Authors:  Raymond J Williams
Journal:  Mol Biotechnol       Date:  2003-03       Impact factor: 2.860

5.  Methodology for Anti-Gene Anti-IGF-I Therapy of Malignant Tumours.

Authors:  Jerzy Trojan; Yuexin X Pan; Ming X Wei; Adama Ly; Alexander Shevelev; Maciej Bierwagen; Marie-Yvonne Ardourel; Ladislas A Trojan; Alvaro Alvarez; Christian Andres; Maria C Noguera; Ignacio Briceno; Beatriz H Aristizabal; Heliodor Kasprzak; Huynh T Duc; Donald D Anthony
Journal:  Chemother Res Pract       Date:  2012-02-14
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.