Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Cyclosporin A: a new advance in transplantation.

Literature DB >> 15226925

Cyclosporin A: a new advance in transplantation.

Abstract

Cyclosporin A (CyA)* has been shown to be a cytostatic drug with apparent specificity for the immune system. At clinical trials, an analysis of the patients showed marked immunosuppressive potency of CyA. This selective anti-T cell agent is described in detail, with studies showing the immunological effects of graft survival in renal transplant patients.

Entities: Chemical Species

Year: 1982 PMID： 15226925 PMCID： PMC351624

Source DB: PubMed Journal: Tex Heart Inst J ISSN： 0730-2347

28 in total

1. Comparative study of in vitro and in vivo drug effects on cell-mediated cytotoxicity.

Authors: J F Borel
Journal: Immunology Date: 1976-10 Impact factor: 7.397

2. Cyclosporin A and dexamethasone suppress T cell responses by selectively acting at distinct sites of the triggering process.

Authors: E L Larsson
Journal: J Immunol Date: 1980-06 Impact factor: 5.422

3. High-performance liquid chromatographic determination of cyclosporin A in human plasma and urine.

Authors: W Niederberger; P Schaub; T Beveridge
Journal: J Chromatogr Date: 1980-06-13

4. Cyclosporin A hepatotoxicity in 66 renal allograft recipients.

Authors: G B Klintmalm; S Iwatsuki; T E Starzl
Journal: Transplantation Date: 1981-12 Impact factor: 4.939

5. Cyclosporin receptor on mouse lymphocytes.

Authors: B Ryffel; P Donatsch; U Götz; M Tschopp
Journal: Immunology Date: 1980-12 Impact factor: 7.397

6. Macrophage-related suppressor cells in human renal transplant recipients.

Authors: J Thomas; F Thomas; S Hoffmann; C Johns; H M Lee
Journal: Surgery Date: 1979-08 Impact factor: 3.982

7. Effect of cyclosporin A on T-dependent and T-independent immunoglobulin synthesis in vitro.

Authors: T Paavonen; P Häyry
Journal: Nature Date: 1980-10-09 Impact factor: 49.962

8. Immune responses to organ allografts. III. Marked decrease in medullary thymocytes and splenic T lymphocytes after cyclosporin A treatment.

Authors: W M Baldwin; I F Hutchinson; C J Meijer; N L Tilney
Journal: Transplantation Date: 1981-02 Impact factor: 4.939

9. Immunosuppressive properties of cyclosporin A (CY-A).

Authors: J F Borel
Journal: Transplant Proc Date: 1980-06 Impact factor: 1.066

10. Use of monoclonal antibodies to T-cell subsets for immunologic monitoring and treatment in recipients of renal allografts.

Authors: A B Cosimi; R B Colvin; R C Burton; R H Rubin; G Goldstein; P C Kung; W P Hansen; F L Delmonico; P S Russell
Journal: N Engl J Med Date: 1981-08-06 Impact factor: 91.245

4 in total

4. Enhanced and sustained topical ocular delivery of cyclosporine A in thermosensitive hyaluronic acid-based in situ forming microgels.

Authors: Yijun Wu; Jing Yao; Jianping Zhou; Fatima Zohra Dahmani
Journal: Int J Nanomedicine Date: 2013-09-20