Literature DB >> 15225948

Surgical management of incompletely excised basal cell carcinomas of the head and neck.

A W Wilson1, G Howsam, V Santhanam, D Macpherson, J Grant, C A Pratt, J V Townend.   

Abstract

We made a retrospective audit of all basal cell carcinomas excised in the Maxillofacial Units at St. Richard's Hospital, Chichester and the Worthing and Southlands NHS Trust between 1990 and 1999. A total of 3795 BCCs were excised. Of these, 3560 were completely excised (93.8%) and 235 were incompletely excised (6.2%), which compares favourably with other series. Of these, 84 patients had further excision, 11 had radiotherapy, and 140 were kept under review. Residual tumour was present in 45% of the re-excised specimens. Of the 140 cases managed by observation, 21% recurred. Notably, 31% of patients in the observation cohort died of other causes without recurrence. Incomplete excision was significantly more likely (P < 0.001) if multiple lesions were excised at the time of operation. Involvement of multiple margins was not a significant risk factor for recurrence in the 'observed' cohort. This study shows that a flexible strategy, which balances observation, further excision and radiotherapy, is superior to any single approach.

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Year:  2004        PMID: 15225948     DOI: 10.1016/j.bjoms.2004.02.030

Source DB:  PubMed          Journal:  Br J Oral Maxillofac Surg        ISSN: 0266-4356            Impact factor:   1.651


  10 in total

1.  Incompletely excised basal cell carcinomas: Our guidelines.

Authors:  P Longhi; M Paola Serra; E Robotti
Journal:  Onco Targets Ther       Date:  2008-07-01       Impact factor: 4.147

2.  Treatment of facial Basal cell carcinoma: a review.

Authors:  Vanessa Smith; Shernaz Walton
Journal:  J Skin Cancer       Date:  2011-04-27

Review 3.  Surgical treatment of basal cell carcinoma: an algorithm based on the literature.

Authors:  Flávio Barbosa Luz; Camila Ferron; Gilberto Perez Cardoso
Journal:  An Bras Dermatol       Date:  2015-06-01       Impact factor: 1.896

4.  Basal cell carcinoma of the head and neck region: a retrospective analysis of completely excised 331 cases.

Authors:  Duriye Deniz Demirseren; Candemir Ceran; Berrak Aksam; Mustafa Erol Demirseren; Ahmet Metin
Journal:  J Skin Cancer       Date:  2014-04-17

Review 5.  [Basal cell basal cell epithelioma of the face: surgical management, about 45 cases and review of the literature].

Authors:  Mohamed Amine Ennouhi; Abdenacer Moussaoui
Journal:  Pan Afr Med J       Date:  2014-09-25

6.  Incomplete excision of basal cell carcinoma (BCC) in the head and neck region: to wait, or not to wait?

Authors:  Jakub Miszczyk; Michał Charytonowicz; Tomasz Dębski; Bartłomiej Noszczyk
Journal:  Postepy Dermatol Alergol       Date:  2017-12-31       Impact factor: 1.837

7.  Recurrence rate of basal cell carcinoma with positive histopathological margins and related risk factors.

Authors:  Fernanda Lara; Jesus Rodriguez Santamaría; Luiz Eduardo Fabricio de Melo Garbers
Journal:  An Bras Dermatol       Date:  2017 Jan-Feb       Impact factor: 1.896

8.  Dermatoscopically narrowed surgical margins for head and neck basal cell carcinoma: A retrospective case-control study.

Authors:  Astrid Herzum; Martina Burlando; Pietro Paolo Tavilla; Claudia Micalizzi; Mattia Fabio Molle; Emanuele Cozzani; Aurora Parodi
Journal:  J Dtsch Dermatol Ges       Date:  2022-05-17       Impact factor: 5.231

Review 9.  Metatypical basal cell carcinoma: a clinical review.

Authors:  Mauro Tarallo; Emanuele Cigna; Riccardo Frati; Sergio Delfino; Daniele Innocenzi; Umberto Fama; Annamaria Corbianco; Nicolò Scuderi
Journal:  J Exp Clin Cancer Res       Date:  2008-11-07

10.  Global incidence of incomplete surgical excision in adult patients with non-melanoma skin cancer: study protocol for a systematic review and meta-analysis of observational studies.

Authors:  Grant S Nolan; Justin C R Wormald; Ailbhe L Kiely; Joshua P Totty; Abhilash Jain
Journal:  Syst Rev       Date:  2020-04-17
  10 in total

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