Literature DB >> 1522422

Psammaplysin C: a new cytotoxic dibromotyrosine-derived metabolite from the marine sponge Druinella (= Psammaplysilla) purpurea.

B R Copp1, C M Ireland, L R Barrows.   

Abstract

The new, cytotoxic dibromotyrosine-derived metabolite psammaplysin C [3], in addition to the two known psammaplysins A [1] and B [2], was isolated from the marine sponge Druinella purpurea. All three compounds were found to possess moderate in vitro cytotoxicity towards the human colon tumor cell-line HCT116.

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Year:  1992        PMID: 1522422     DOI: 10.1021/np50084a021

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  7 in total

Review 1.  The marine bromotyrosine derivatives.

Authors:  Jiangnan Peng; Jing Li; Mark T Hamann
Journal:  Alkaloids Chem Biol       Date:  2005

2.  Oxonium Ion Mediated Synthesis of 4-Substituted Spiro-Isoxazolines.

Authors:  Eric McClendon; Ann O Omollo; Edward J Valente; Ashton T Hamme
Journal:  Tetrahedron Lett       Date:  2009-02-04       Impact factor: 2.415

3.  Twilight zone sponges from Guam yield theonellin isocyanate and psammaplysins I and J.

Authors:  Anthony D Wright; Peter J Schupp; Jan-Philipp Schrör; Anna Engemann; Sven Rohde; Dovi Kelman; Nicole de Voogd; Anthony Carroll; Cherie A Motti
Journal:  J Nat Prod       Date:  2012-01-11       Impact factor: 4.050

Review 4.  The Oxepane Motif in Marine Drugs.

Authors:  Héctor Barbero; Carlos Díez-Poza; Asunción Barbero
Journal:  Mar Drugs       Date:  2017-11-15       Impact factor: 5.118

5.  Cytotoxic Psammaplysin Analogues from the Verongid Red Sea Sponge Aplysinella Species.

Authors:  Lamiaa A Shaala; Diaa T A Youssef
Journal:  Biomolecules       Date:  2019-12-08

6.  Psammaceratin A: A Cytotoxic Psammaplysin Dimer Featuring an Unprecedented (2Z,3Z)-2,3-Bis(aminomethylene)succinamide Backbone from the Red Sea Sponge Pseudoceratina arabica.

Authors:  Diaa T A Youssef; Hani Z Asfour; Lamiaa A Shaala
Journal:  Mar Drugs       Date:  2021-07-29       Impact factor: 5.118

7.  Synthesis and biological evaluation of fluoro-substituted spiro-isoxazolines as potential anti-viral and anti-cancer agents.

Authors:  Prasanta Das; Sarah Boone; Dipanwita Mitra; Lindsay Turner; Ritesh Tandon; Drazen Raucher; Ashton T Hamme
Journal:  RSC Adv       Date:  2020-08-17       Impact factor: 4.036

  7 in total

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