Literature DB >> 15223946

High rates of neurological improvement following severe traumatic pediatric spinal cord injury.

Michael Y Wang1, Daniel J Hoh, Scott P Leary, Pamela Griffith, J Gordon McComb.   

Abstract

STUDY
DESIGN: Retrospective single-center study
OBJECTIVES: To determine the long-term outcome of pediatric spinal cord injuries SUMMARY OF BACKGROUND DATA: Spinal cord injuries are uncommon events in the pediatric population. In the few large series reported in the literature, recovery of neurologic function was demonstrated after mild injuries but was rare after severe injuries.
METHODS: A total of 4,876 cases of pediatric trauma treated at the Children's Hospital of Los Angeles over a 9-year period (1993-2001) were reviewed. During the study period, 91 cases of spinal cord or spinal column injury were identified, and 30 cases involving a spinal cord injury were identified. Cauda equina injuries were excluded. Seven craniocervical, 12 cervical, 5 thoracic, and 6 thoracolumbar cases were identified. There were 6 cases of spinal cord injury without radiographic abnormality. Eight of the 30 patients received methylprednisolone at the time of admission. Follow-up ranged from 2 to 54 (mean = 19) months.
RESULTS: Twenty patients presented with complete injuries (ASIA grade A). Of these, 7 died, 7 had no neurologic recovery, and 6 experienced neurologic improvement. Five of these six eventually became ambulatory with functional gains occurring over a 4- to 50-week period. None of these 5 patients was found to have spinal cord injury without radiographic abnormality. Of the remaining 10 patients (grades B-D), 8 experienced improvements in neurologic function. Cervical dislocation injuries were associated with a low likelihood of neurologic improvement and atlanto-occipital injuries were associated with early death.
CONCLUSIONS: Recovery of neurologic function following severe traumatic spinal cord injury occurs with a significantly greater incidence in children than adults, and these improvements can occur over a prolonged postinjury period.

Entities:  

Mesh:

Year:  2004        PMID: 15223946     DOI: 10.1097/01.brs.0000129026.03194.0f

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  18 in total

1.  Paediatric cervical spine injures. Nineteen years experience of a single centre.

Authors:  Manuel Ribeiro da Silva; Daniela Linhares; Pedro Cacho Rodrigues; Eurico Lisboa Monteiro; Manuel Santos Carvalho; Pedro Negrão; Rui Peixoto Pinto; Nuno Neves
Journal:  Int Orthop       Date:  2016-04-06       Impact factor: 3.075

2.  Loss of correction in spinal cord injury-related scoliosis after pedicle screw fixation.

Authors:  Mina G Safain; Steven Hwang; Joseph King; Patrick Cahill; Amer Samdani
Journal:  Childs Nerv Syst       Date:  2013-11-20       Impact factor: 1.475

Review 3.  Spinal cord injury in the pediatric population: a systematic review of the literature.

Authors:  Stefan Parent; Jean-Marc Mac-Thiong; Marjolaine Roy-Beaudry; Jose Felix Sosa; Hubert Labelle
Journal:  J Neurotrauma       Date:  2011-06-09       Impact factor: 5.269

Review 4.  Spinal cord injuries without radiologic abnormality in children: a systematic review.

Authors:  T Carroll; C D Smith; X Liu; B Bonaventura; N Mann; J Liu; N A Ebraheim
Journal:  Spinal Cord       Date:  2015-07-14       Impact factor: 2.772

Review 5.  A review: the role of high dose methylprednisolone in spinal cord trauma in children.

Authors:  Janine N Pettiford; Jai Bikhchandani; Daniel J Ostlie; Shawn D St Peter; Ronald J Sharp; David Juang
Journal:  Pediatr Surg Int       Date:  2011-10-13       Impact factor: 1.827

6.  Psychosocial and Health Outcomes of Adults With Violently Acquired Pediatric Spinal Cord Injury.

Authors:  Alicia M January; Suzanne Kirk; Kathy Zebracki; Kathleen M Chlan; Lawrence C Vogel
Journal:  Top Spinal Cord Inj Rehabil       Date:  2018-02-12

7.  Severity of spinal cord injury in adult and infant rats after vertebral dislocation depends upon displacement but not speed.

Authors:  Ngee-Soon Stephen Lau; Catherine A Gorrie; Jie Yu Chia; Lynne E Bilston; Elizabeth C Clarke
Journal:  J Neurotrauma       Date:  2013-07-16       Impact factor: 5.269

8.  Motor scores on the functional independence measure after pediatric spinal cord injury.

Authors:  D D Allen; M J Mulcahey; S M Haley; M J Devivo; L C Vogel; C McDonald; T Duffy; R R Betz
Journal:  Spinal Cord       Date:  2008-08-05       Impact factor: 2.772

9.  Morbidity after traumatic spinal injury in pediatric and adolescent sports-related trauma.

Authors:  Saksham Gupta; Blake M Hauser; Mark M Zaki; Edward Xu; David J Cote; Yi Lu; John H Chi; Michael Groff; Ayaz M Khawaja; Mitchel B Harris; Timothy R Smith; Hasan A Zaidi
Journal:  J Neurosurg Spine       Date:  2019-12-27

10.  Spinal cord trauma in children under 10 years of age: clinical characteristics and prevention.

Authors:  Ricardo de Amoreira Gepp; Luiz Guilherme Nadal
Journal:  Childs Nerv Syst       Date:  2012-07-14       Impact factor: 1.475

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