BACKGROUND AND AIM OF THE STUDY: The study aim was to examine results after stentless mitral valve (SMV) replacement (Quattro) and restitution of physiological cardiac rhythm by intraoperative left atrial ablation therapy. METHODS: Twenty patients (13 females; mean age 69.7 +/- 5.9 years) with severe degenerative mitral valve disease (six with valve stenosis, six with valve incompetence, eight with combined lesion) were prospectively evaluated since 1998. The mean NYHA functional class was 3.2 +/- 0.4, and cardiac index 1.8 +/- 0.5 l/min/m2. Ablation therapy was performed by inducing left atrial linear lesion lines to avoid reentrant circuits. RESULTS: Surgery was performed using conventional sternotomy (n = 10) or lateral minithoractomy (n = 10). Sinus rhythm was successfully restituted in 17 patients either postoperatively or in the long term (success rate 85%). However, three patients required DDD-pacemaker implantation, and another three had to be discharged with persistent atrial fibrillation. Intermittent medical therapy (sotalol or amiodarone) was required in nine patients postoperatively, in four patients at six months, and in two patients at one-year follow up. One patient was reoperated on for paravalvular leak after one year, but subsequently died due to sepsis. In the other patients, echocardiographic control proved good SMV function with atrial contraction. CONCLUSION: Restitution of physiological cardiac function is possible by combined stentless MV implantation and left atrial ablation therapy. A persistent benefit, without need for additional re-intervention, was shown at mid-term follow up.
BACKGROUND AND AIM OF THE STUDY: The study aim was to examine results after stentless mitral valve (SMV) replacement (Quattro) and restitution of physiological cardiac rhythm by intraoperative left atrial ablation therapy. METHODS: Twenty patients (13 females; mean age 69.7 +/- 5.9 years) with severe degenerative mitral valve disease (six with valve stenosis, six with valve incompetence, eight with combined lesion) were prospectively evaluated since 1998. The mean NYHA functional class was 3.2 +/- 0.4, and cardiac index 1.8 +/- 0.5 l/min/m2. Ablation therapy was performed by inducing left atrial linear lesion lines to avoid reentrant circuits. RESULTS: Surgery was performed using conventional sternotomy (n = 10) or lateral minithoractomy (n = 10). Sinus rhythm was successfully restituted in 17 patients either postoperatively or in the long term (success rate 85%). However, three patients required DDD-pacemaker implantation, and another three had to be discharged with persistent atrial fibrillation. Intermittent medical therapy (sotalol or amiodarone) was required in nine patients postoperatively, in four patients at six months, and in two patients at one-year follow up. One patient was reoperated on for paravalvular leak after one year, but subsequently died due to sepsis. In the other patients, echocardiographic control proved good SMV function with atrial contraction. CONCLUSION: Restitution of physiological cardiac function is possible by combined stentless MV implantation and left atrial ablation therapy. A persistent benefit, without need for additional re-intervention, was shown at mid-term follow up.