Literature DB >> 15220537

Analyzing cell cycle checkpoints after ionizing radiation.

Bo Xu1, Michael B Kastan.   

Abstract

Several methods to measure cell cycle perturbation after exposure to ionizing radiation are presented in this chapter. These methods include the G1 checkpoint assay by 5' bromode-oxyuridine (BrdUrd) labeling followed by flow cytometric analysis, the S-phase checkpoint assay by measuring DNA synthesis in response to ionizing radiation, and the G2/M checkpoint assay by quantitating histone H3 phosphorylation after ionizing radiation.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15220537     DOI： 10.1385/1-59259-811-0:283

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  14 in total

1.  Specific role of Chk1 phosphorylations in cell survival and checkpoint activation.

Authors:  Hiroyuki Niida; Yuko Katsuno; Birendranath Banerjee; M Prakash Hande; Makoto Nakanishi
Journal:  Mol Cell Biol       Date:  2007-01-22       Impact factor: 4.272

2.  Protein Phosphatase 2A Inhibition with LB100 Enhances Radiation-Induced Mitotic Catastrophe and Tumor Growth Delay in Glioblastoma.

Authors:  Ira K Gordon; Jie Lu; Christian A Graves; Kristin Huntoon; Jason M Frerich; Ryan H Hanson; Xiaoping Wang; Christopher S Hong; Winson Ho; Michael J Feldman; Barbara Ikejiri; Kheem Bisht; Xiaoyuan S Chen; Anita Tandle; Chunzhang Yang; W Tristram Arscott; Donald Ye; John D Heiss; Russell R Lonser; Kevin Camphausen; Zhengping Zhuang
Journal:  Mol Cancer Ther       Date:  2015-05-04       Impact factor: 6.261

3.  A novel function of HER2/Neu in the activation of G2/M checkpoint in response to γ-irradiation.

Authors:  Y Yan; A L Hein; P M Greer; Z Wang; R H Kolb; S K Batra; K H Cowan
Journal:  Oncogene       Date:  2014-06-09       Impact factor: 9.867

4.  A Novel Role of Chromodomain Protein CBX8 in DNA Damage Response.

Authors:  Jay Oza; Bratati Ganguly; Atul Kulkarni; Vasudeva Ginjala; Ming Yao; Shridar Ganesan
Journal:  J Biol Chem       Date:  2016-08-23       Impact factor: 5.157

5.  Protein phosphatase 2A has an essential role in the activation of gamma-irradiation-induced G2/M checkpoint response.

Authors:  Y Yan; P T Cao; P M Greer; E S Nagengast; R H Kolb; M C Mumby; K H Cowan
Journal:  Oncogene       Date:  2010-05-24       Impact factor: 9.867

6.  The human LINE-1 retrotransposon creates DNA double-strand breaks.

Authors:  Stephen L Gasior; Timothy P Wakeman; Bo Xu; Prescott L Deininger
Journal:  J Mol Biol       Date:  2006-02-09       Impact factor: 5.469

7.  Mitochondria-targeted antioxidant enzyme activity regulates radioresistance in human pancreatic cancer cells.

Authors:  Carolyn J Fisher; Prabhat C Goswami
Journal:  Cancer Biol Ther       Date:  2008-08-13       Impact factor: 4.742

8.  Estrogen inhibits ATR signaling to cell cycle checkpoints and DNA repair.

Authors:  Ali Pedram; Mahnaz Razandi; Albert J Evinger; Eva Lee; Ellis R Levin
Journal:  Mol Biol Cell       Date:  2009-05-28       Impact factor: 4.138

9.  Radiosensitization by the novel DNA intercalating agent vosaroxin.

Authors:  Ira K Gordon; Christian Graves; Whoon J Kil; Tamalee Kramp; Philip Tofilon; Kevin Camphausen
Journal:  Radiat Oncol       Date:  2012-02-27       Impact factor: 3.481

10.  ERK1/2 signaling plays an important role in topoisomerase II poison-induced G2/M checkpoint activation.

Authors:  Ryan H Kolb; Patrick M Greer; Phu T Cao; Kenneth H Cowan; Ying Yan
Journal:  PLoS One       Date:  2012-11-16       Impact factor: 3.240
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.