H Nakayama1, H Enzan, M Yamamoto, E Miyazaki, W Yasui. 1. Department of Molecular Pathology, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi Minami-ku, Hiroshima 734-8551, Japan. nakayamh@hiroshima-u.ac.jp
Abstract
AIMS: To investigate the smooth muscle nature of the stromal cells in the capsule of hepatocellular carcinomas. METHODS: Immunohistochemical analysis using monoclonal antibody to high molecular weight caldesmon (HCD), a highly specific marker for smooth muscle cells, was performed in 33 encapsulated hepatocellular carcinomas and adjacent hepatic tissues. RESULTS: HCD positive stromal cells were detected in the capsule of 21 of the 33 hepatocellular carcinomas examined. CONCLUSIONS: The capsule of hepatocellular carcinomas contains smooth muscle cells.
AIMS: To investigate the smooth muscle nature of the stromal cells in the capsule of hepatocellular carcinomas. METHODS: Immunohistochemical analysis using monoclonal antibody to high molecular weight caldesmon (HCD), a highly specific marker for smooth muscle cells, was performed in 33 encapsulated hepatocellular carcinomas and adjacent hepatic tissues. RESULTS:HCD positive stromal cells were detected in the capsule of 21 of the 33 hepatocellular carcinomas examined. CONCLUSIONS: The capsule of hepatocellular carcinomas contains smooth muscle cells.
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