Literature DB >> 15220373

The diagnosis of hepatosplenic candidiasis by DNA analysis of tissue biopsy and serum.

A Kirby1, C Chapman, C Hassan, J Burnie.   

Abstract

Hepatosplenic candidiasis is traditionally diagnosed by blood culture, magnetic resonance imaging (MRI), and histological analysis. The limitations of these methods include: low sensitivity (blood culture) and failure to isolate the organism (MRI/histology). This report describes a case of hepatosplenic candidiasis diagnosed by simultaneous polymerase chain reaction (PCR) analysis of liver biopsy and serum. PCR of biopsy and/or serum may offer a sensitive and specific diagnostic test for hepatosplenic candidiasis. Candida species can be identified, which helps guide antifungal chemotherapy, an important aspect in this difficult to treat infection.

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Year:  2004        PMID： 15220373      PMCID： PMC1770349          DOI： 10.1136/jcp.2003.015347

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  10 in total

1.  In vitro activity of the new echinocandin antifungal, MK-0991, against common and uncommon clinical isolates of Candida species.

Authors:  F Barchiesi; A M Schimizzi; A W Fothergill; G Scalise; M G Rinaldi
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1999-04       Impact factor: 3.267

2.  Echinocandins--an advance in the primary treatment of invasive candidiasis.

Authors:  Thomas J Walsh
Journal:  N Engl J Med       Date:  2002-12-19       Impact factor: 91.245

3.  Rapid identification of candida species by TaqMan PCR.

Authors:  M Guiver; K Levi; B A Oppenheim
Journal:  J Clin Pathol       Date:  2001-05       Impact factor: 3.411

Review 4.  Clinical, cellular, and molecular factors that contribute to antifungal drug resistance.

Authors:  T C White; K A Marr; R A Bowden
Journal:  Clin Microbiol Rev       Date:  1998-04       Impact factor: 26.132

5.  PCR-restriction enzyme analysis for detection of Candida DNA in blood from febrile patients with hematological malignancies.

Authors:  G Morace; L Pagano; M Sanguinetti; B Posteraro; L Mele; F Equitani; G D'Amore; G Leone; G Fadda
Journal:  J Clin Microbiol       Date:  1999-06       Impact factor: 5.948

6.  Rapid identification of fungi by using the ITS2 genetic region and an automated fluorescent capillary electrophoresis system.

Authors:  C Y Turenne; S E Sanche; D J Hoban; J A Karlowsky; A M Kabani
Journal:  J Clin Microbiol       Date:  1999-06       Impact factor: 5.948

7.  Hepatosplenic candidiasis in patients with acute leukaemia.

Authors:  S Sallah; R C Semelka; R Wehbie; W Sallah; N P Nguyen; P Vos
Journal:  Br J Haematol       Date:  1999-09       Impact factor: 6.998

8.  Trends in frequency and in vitro susceptibilities to antifungal agents, including voriconazole and anidulafungin, of Candida bloodstream isolates. Results from a six-year study (1996-2001).

Authors:  F Marco; C Danés; M Almela; A Jurado; J Mensa; J Puig de la Bellacasa; M Espasa; J A Martínez; M T Jiménez de Anta
Journal:  Diagn Microbiol Infect Dis       Date:  2003-08       Impact factor: 2.803

9.  Comparison of caspofungin and amphotericin B for invasive candidiasis.

Authors:  Jorge Mora-Duarte; Robert Betts; Coleman Rotstein; Arnaldo Lopes Colombo; Luis Thompson-Moya; Juanita Smietana; Robert Lupinacci; Carole Sable; Nicholas Kartsonis; John Perfect
Journal:  N Engl J Med       Date:  2002-12-19       Impact factor: 91.245

10.  In vitro activities of voriconazole, posaconazole, and four licensed systemic antifungal agents against Candida species infrequently isolated from blood.

Authors:  M A Pfaller; D J Diekema; S A Messer; L Boyken; R J Hollis; R N Jones
Journal:  J Clin Microbiol       Date:  2003-01       Impact factor: 5.948
  10 in total
  2 in total

Review 1.  Polymerase chain reaction-based assays for the diagnosis of invasive fungal infections.

Authors:  Themistoklis K Kourkoumpetis; Beth Burgwyn Fuchs; Jeffrey J Coleman; Athanasios Desalermos; Eleftherios Mylonakis
Journal:  Clin Infect Dis       Date:  2012-02-23       Impact factor: 9.079

2.  Utility of Panfungal PCR in the diagnosis of invasive fungal infections in febrile neutropenia.

Authors:  Sujay Srinivas; Pushpa Kumari; Dipendra Kumar Gupta
Journal:  J Family Med Prim Care       Date:  2021-07-30
  2 in total

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