Literature DB >> 15218406

Pharmacological management of persistent pain in older patients.

Perry G Fine1.   

Abstract

OBJECTIVES: The purpose of this manuscript is to foster understanding of the unique attributes of aging as they relate to the treatment of persistent pain in order to improve care of older patients.
METHODS: : A thorough review of pertinent recent literature, including clinical guidelines, provided the materials from which this synthesis is drawn.
RESULTS: Several unique attributes of aging are identified that should be taken into account in order to provide safe and effective pharmacotherapy for older patients with persistent pain. DISCUSSION: Adherence to contemporary clinical guidelines should serve to promote improved outcomes in older patients who suffer from ongoing and debilitating pain. Since outcomes studies are lacking, attention to principles of care as they apply to this particular population is advised. Since each patient's experience and response to drug therapy will be unique, individualized assessment that incorporates an analysis of the patient's physiological state (comorbidities and concurrent drug therapies), a determination of realistic goals, and monitoring of outcomes on a regular basis will provide the optimum balance between benefits and risks of analgesic pharmacotherapy.

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Year:  2004        PMID: 15218406     DOI: 10.1097/00002508-200407000-00003

Source DB:  PubMed          Journal:  Clin J Pain        ISSN: 0749-8047            Impact factor:   3.442


  6 in total

1.  Age and gender trends in long-term opioid analgesic use for noncancer pain.

Authors:  Cynthia I Campbell; Constance Weisner; Linda Leresche; G Thomas Ray; Kathleen Saunders; Mark D Sullivan; Caleb J Banta-Green; Joseph O Merrill; Michael J Silverberg; Denise Boudreau; Derek D Satre; Michael Von Korff
Journal:  Am J Public Health       Date:  2010-08-19       Impact factor: 9.308

Review 2.  A comparison of long- and short-acting opioids for the treatment of chronic noncancer pain: tailoring therapy to meet patient needs.

Authors:  Charles E Argoff; Daniel I Silvershein
Journal:  Mayo Clin Proc       Date:  2009-07       Impact factor: 7.616

3.  Effects of chronic fentanyl administration on physical performance of aged rats.

Authors:  Jeremiah D Mitzelfelt; Jameson P Dupree; Dong-oh Seo; Christy S Carter; Drake Morgan
Journal:  Exp Gerontol       Date:  2010-10-15       Impact factor: 4.032

Review 4.  Pharmacological management of cancer pain in the elderly.

Authors:  Sebastiano Mercadante; Edoardo Arcuri
Journal:  Drugs Aging       Date:  2007       Impact factor: 3.923

5.  Safety and efficacy of duloxetine treatment in older and younger patients with osteoarthritis knee pain: a post hoc, subgroup analysis of two randomized, placebo-controlled trials.

Authors:  Joseph L Micca; Dustin Ruff; Jonna Ahl; Madelaine M Wohlreich
Journal:  BMC Musculoskelet Disord       Date:  2013-04-17       Impact factor: 2.362

6.  Pain management in the elderly: transdermal fentanyl for the treatment of pain caused by osteoarthritis of the knee and hip.

Authors:  Sylwester Mordarski
Journal:  Biomed Res Int       Date:  2014-01-05       Impact factor: 3.411

  6 in total

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