Literature DB >> 15217298

Botryllamides E-H, four new tyrosine derivatives from the ascidian Botrylloides tyreum.

M Rama Rao1, D John Faulkner.   

Abstract

A specimen of the ascidian Botrylloides tyreum from Palau contained the known metabolites botryllamides A (5) and C (7) together with four new tyrosine derivatives, botryllamides E-H (1-4), the structures of which were elucidated by interpretation of spectroscopic data. The botryllamides exhibited weak cytotoxicity against the HCT-116 cell line.

Entities:  

Mesh:

Substances:

Year:  2004        PMID: 15217298     DOI: 10.1021/np0499618

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  5 in total

1.  Botryllamides: natural product inhibitors of ABCG2.

Authors:  Curtis J Henrich; Robert W Robey; Kentaro Takada; Heidi R Bokesch; Susan E Bates; Suneet Shukla; Suresh V Ambudkar; James B McMahon; Kirk R Gustafson
Journal:  ACS Chem Biol       Date:  2009-08-21       Impact factor: 5.100

Review 2.  Marine natural products as breast cancer resistance protein inhibitors.

Authors:  Lilia Cherigo; Dioxelis Lopez; Sergio Martinez-Luis
Journal:  Mar Drugs       Date:  2015-04-03       Impact factor: 5.118

Review 3.  Immunity in Protochordates: The Tunicate Perspective.

Authors:  Nicola Franchi; Loriano Ballarin
Journal:  Front Immunol       Date:  2017-06-09       Impact factor: 7.561

Review 4.  Natural Products Diversity of Marine Ascidians (Tunicates; Ascidiacea) and Successful Drugs in Clinical Development.

Authors:  Satheesh Kumar Palanisamy; N M Rajendran; Angela Marino
Journal:  Nat Prod Bioprospect       Date:  2017-01-17

5.  Botryllamide G is an ABCG2 inhibitor that improves lapatinib delivery in mouse brain.

Authors:  Jonathan D Strope; Cody J Peer; Tristan M Sissung; O Morgan Hall; Phoebe A Huang; Emily M Harris; Kirk R Gustafson; Curtis J Henrich; Dina M Sigano; Gary T Pauly; Joel P Schneider; Susan E Bates; William D Figg
Journal:  Cancer Biol Ther       Date:  2019-11-10       Impact factor: 4.742

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.