Literature DB >> 15216070

THEORETICAL DESIGN CONSIDERATIONS AND PHYSIOLOGIC PERFORMANCE CRITERIA FOR AN IMPROVED INTRACORPOREAL (ABDOMINAL) ELECTRICALLY ACTUATED LONG-TERM LEFT VENTRICULAR ASSIST DEVICE ("E-TYPE" ALVAD) OR PARTIAL ARTIFICIAL HEART.

Stephen R. Igo1, C Wayne Hibbs, John M. Fuqua, Ruben Trono, Charles H. Edmonds, John C. Norman.   

Abstract

Our laboratories are engaged in the design of a clinically-oriented electrically actuated long-term intracorporeal (abdominal) left ventricular assist device ("E-type" ALVAD) or partial artificial heart. This infradiaphragmatic blood pump is designed to be powered by implantable electrical to mechanical energy converter systems. THE FOLLOWING ANALYSES WERE UNDERTAKEN TO: [List: see text] The proposed "E-type" ALVAD should be capable of pumping 4-7 liters per minute at heart rates of 75-100 beats per minute during rest, and 10 liters per minute at rates of 120 beats per minute during moderate exercise. These performance levels should be exceeded with a maximum device stroke volume of 85-90 ml and a mean pump inflow (filling) impedance of </= 0.072 gm/sec/cm(-5).

Entities:  

Year:  1978        PMID： 15216070      PMCID： PMC287725     

Source DB:  PubMed          Journal:  Cardiovasc Dis        ISSN： 0093-3546


  12 in total

1.  A pusher plate pump for tatally implantable left ventricular assist device systems.

Authors:  B D Daly; K G Hagen; J M Fuqua; S R Igo; F N Huffman; J C Norman
Journal:  J Surg Res       Date:  1975-06       Impact factor: 2.192

2.  IMPLICATIONS OF STUDIES OF VASCULAR IMPEDANCE FOR ASSESSMENT OF LEFT VENTRICULAR FUNCTION.

Authors:  William E. Walker
Journal:  Cardiovasc Dis       Date:  1974

3.  An abdominal left ventricular assist device: preclinical studies.

Authors:  W J Robinson; B S Benedict; D T Daly; D A Hughes; J J Migliore; C W Hibbs; S R Igo; J C Norman
Journal:  Ann Thorac Surg       Date:  1975-05       Impact factor: 4.330

4.  Chronic evaluations of ventricular ejection phase dynamics during abdominal left ventricular assist device (ALVAD) pumping in the awake, unanesthetized calf.

Authors:  S R Igo; C W Hibbs; J M Fuqua; M G Walker; J G Naifeh; J C Norman
Journal:  Trans Am Soc Artif Intern Organs       Date:  1976

5.  An abdominal left ventricular assist device (ALVAD): chronic hemodynamic analyses in the calf.

Authors:  W J Robinson; S R Igo; B D Daly; J J Migliore; D A Hughes; C H Edmonds; J M Fuqua; F N Huffman; J C Norman
Journal:  Trans Am Soc Artif Intern Organs       Date:  1974

6.  An electrically actuated left ventricular assist device (E-A LVAD) in vivo testing.

Authors:  J G Aldrich; J A Chambers; B D Daly; J J Migliore; P Newgard; F N Huffman; J C Norman
Journal:  Trans Am Soc Artif Intern Organs       Date:  1974

7.  Nuclear-fueled circulatory support systems XII: current status.

Authors:  D A Hughes; R J Faeser; B D Daly; C H Edmonds; L V Feigenbutz; S R Igo; K Hagen; J J Migliore; A E Ruggles; W J Robinson; F N Huffman; J C Norman
Journal:  Trans Am Soc Artif Intern Organs       Date:  1974

8.  Hemodynamic and metabolic responses to vasodilator therapy in acute myocardial infarction.

Authors:  K Chatterjee; W W Parmley; W Ganz; J Forrester; P Walinsky; C Crexells; H J Swan
Journal:  Circulation       Date:  1973-12       Impact factor: 29.690

9.  Effects of an abdominal left ventricular assist device on myocardial oxygen supply/demand ratios in normally perfused and ischemic bovine myocardium.

Authors:  D A Hughes; S R Igo; B D Daly; J J Migliore; J C Norman
Journal:  Ann Thorac Surg       Date:  1975-03       Impact factor: 4.330

10.  AN INTRACORPOREAL (ABDOMINAL) LEFT VENTRICULAR ASSIST DEVICE [ALVAD], XXX: CLINICAL READINESS AND INITIAL TRIALS IN MAN.

Authors:  John C. Norman
Journal:  Cardiovasc Dis       Date:  1976
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  1 in total

1.  Use of a composite Biomer-butyl rubber/Biomer material to prevent transdiaphragmatic water permeation during long-term, electrically-actuated left ventricular assist device (LVAD) pumping.

Authors:  Michael G. McGee; Michael Szycher; Stephen A. Turner; Warren Clay; Ruben Trono; John M. Fuqua; John C. Norman
Journal:  Cardiovasc Dis       Date:  1980-09
  1 in total

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