Literature DB >> 15215137

Micafungin enhances neutrophil fungicidal functions against Candida pseudohyphae.

Cristina Gil-Lamaignere1, Stefanie Salvenmoser, Regina Hess, Frank-Michael C Müller.   

Abstract

We evaluated the effect of the combination of micafungin and polymorphonuclear leukocytes (PMN) against hyphae of Candida albicans and Candida dubliniensis. Micafungin enhanced the PMN oxidative burst dose dependently. The combination was synergistic (C. albicans) or additive (C. dubliniensis); when PMN were pretreated with granulocyte-macrophage colony-stimulating factor, the combination was more effective.

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Year:  2004        PMID： 15215137      PMCID： PMC434213          DOI： 10.1128/AAC.48.7.2730-2732.2004

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

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Review 7.  Comparison of the epidemiology, drug resistance mechanisms, and virulence of Candida dubliniensis and Candida albicans.

Authors:  Derek J Sullivan; Gary P Moran; Emmanuelle Pinjon; Asmaa Al-Mosaid; Cheryl Stokes; Claire Vaughan; David C Coleman
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  10 in total
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Review 3.  Micafungin: a review of its use in adults for the treatment of invasive and oesophageal candidiasis, and as prophylaxis against Candida infections.

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  5 in total

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