K Malaker1, K Vijayraghavan, I Hodson, T Al Yafi. 1. Princess Norah Oncology Centre, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, Kingdom of Saudi Arabia. kamal_malaker@hotmail.com
Abstract
AIMS: The purpose of the study was to review retrospectively the role of primary radiotherapy for unresectable keloids. MATERIALS AND METHODS: Kilovoltage X-rays and mega-voltage electron beams were used to irradiate large bulky unresectable keloids. A total of 3750 cGy was given in five once-weekly fractions, over a period of 5 weeks. Eighty-six keloids in 64 patients were treated between 1977 and 2002. RESULTS: Ninety-seven per cent of this cohort had significant regression, and 3% had partial regression 18 months after completing radiotherapy. Both acute and long-term reactions were acceptable, and so far none of the patients have been reported as having cancer of any sort. Sixty-three per cent of the patients surveyed were very happy with the outcome of their treatment. CONCLUSION: Unresectable bulky symptomatic keloids can be satisfactorily treated with hypo-fractionated radiotherapy primarily using either kilovoltage X-rays or electron beams without significant short- or long-term side-effects.
AIMS: The purpose of the study was to review retrospectively the role of primary radiotherapy for unresectable keloids. MATERIALS AND METHODS: Kilovoltage X-rays and mega-voltage electron beams were used to irradiate large bulky unresectable keloids. A total of 3750 cGy was given in five once-weekly fractions, over a period of 5 weeks. Eighty-six keloids in 64 patients were treated between 1977 and 2002. RESULTS: Ninety-seven per cent of this cohort had significant regression, and 3% had partial regression 18 months after completing radiotherapy. Both acute and long-term reactions were acceptable, and so far none of the patients have been reported as having cancer of any sort. Sixty-three per cent of the patients surveyed were very happy with the outcome of their treatment. CONCLUSION: Unresectable bulky symptomatic keloids can be satisfactorily treated with hypo-fractionated radiotherapy primarily using either kilovoltage X-rays or electron beams without significant short- or long-term side-effects.
Authors: A Montero Luis; R Hernanz de Lucas; A Hervás Morón; E Fernández Lizarbe; S Sancho García; C Vallejo Ocaña; A Polo Rubio; A Ramos Aguerri Journal: Clin Transl Oncol Date: 2008-06 Impact factor: 3.405
Authors: Kristin Jones; Clifton D Fuller; Join Y Luh; Craig C Childs; Alexander R Miller; Anthony W Tolcher; Terence S Herman; Charles R Thomas Journal: BMC Dermatol Date: 2006-04-19
Authors: Ali Akbar Mohammadi; Mohammad Mohammadian Panah; Mohammad Reza Pakyari; Raziyeh Tavakol; Iman Ahrary; Seyed Morteza Seyed Jafari; Maryam Sharifian Journal: World J Plast Surg Date: 2013-06