Literature DB >> 15213178

Expression of a C terminally truncated form of pertussis toxin S1 subunit effectively induces protection against pertussis toxin following DNA-based immunization.

Kazunari Kamachi1, Yoshichika Arakawa.   

Abstract

Four plasmids encoding different C terminally and N terminally truncated pertussis toxin S1 subunits of Bordetella pertussis were constructed and tested for inducibility of protection against pertussis toxin in mice after DNA-based immunization. The region encoding an N-terminal 180-amino-acid fragment of the S1 subunit had the most potent ability to induce protective immunity.

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Year:  2004        PMID： 15213178      PMCID： PMC427423          DOI： 10.1128/IAI.72.7.4293-4296.2004

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  24 in total

1.  Neutralizing antibodies and immunoprotection against pertussis and tetanus obtained by use of a recombinant pertussis toxin-tetanus toxin fusion protein.

Authors:  P Boucher; H Sato; Y Sato; C Locht
Journal:  Infect Immun       Date:  1994-02       Impact factor: 3.441

2.  Roles of the disulfide bond and the carboxy-terminal region of the S1 subunit in the assembly and biosynthesis of pertussis toxin.

Authors:  R Antoine; C Locht
Journal:  Infect Immun       Date:  1990-06       Impact factor: 3.441

3.  Expression and immunogenicity of pertussis toxin S1 subunit-tetanus toxin fragment C fusions in Salmonella typhi vaccine strain CVD 908.

Authors:  E M Barry; O Gomez-Duarte; S Chatfield; R Rappuoli; M Pizza; G Losonsky; J Galen; M M Levine
Journal:  Infect Immun       Date:  1996-10       Impact factor: 3.441

4.  Mass vaccination of children with pertussis toxoid--decreased incidence in both vaccinated and nonvaccinated persons.

Authors:  J Taranger; B Trollfors; E Bergfors; N Knutsson; V Sundh; T Lagergård; L Lind-Brandberg; G Zackrisson; J White; H Cicirello; J Fusco; J B Robbins
Journal:  Clin Infect Dis       Date:  2001-08-22       Impact factor: 9.079

5.  Oral colonization and immune responses to Streptococcus gordonii expressing a pertussis toxin S1 fragment in mice.

Authors:  Song F Lee; S A Halperin; H Wang; A MacArthur
Journal:  FEMS Microbiol Lett       Date:  2002-03-05       Impact factor: 2.742

6.  Recombinant Mycobacterium bovis BCG expressing pertussis toxin subunit S1 induces protection against an intracerebral challenge with live Bordetella pertussis in mice.

Authors:  I P Nascimento; W O Dias; R P Mazzantini; E N Miyaji; M Gamberini; W Quintilio; V C Gebara; D F Cardoso; P L Ho; I Raw; N Winter; B Gicquel; R Rappuoli; L C Leite
Journal:  Infect Immun       Date:  2000-09       Impact factor: 3.441

7.  Surface expression of a protective recombinant pertussis toxin S1 subunit fragment in Streptococcus gordonii.

Authors:  S F Lee; R J March; S A Halperin; G Faulkner; L Gao
Journal:  Infect Immun       Date:  1999-03       Impact factor: 3.441

8.  Purification and immunogenicity of a recombinant Bordetella pertussis S1S3FHA fusion protein expressed by Streptococcus gordonii.

Authors:  Song F Lee; Scott A Halperin; Jennifer B Knight; Aaron Tait
Journal:  Appl Environ Microbiol       Date:  2002-09       Impact factor: 4.792

9.  Assignment of functional domains involved in ADP-ribosylation and B-oligomer binding within the carboxyl terminus of the S1 subunit of pertussis toxin.

Authors:  K M Krueger; J T Barbieri
Journal:  Infect Immun       Date:  1994-05       Impact factor: 3.441

10.  A placebo-controlled trial of a pertussis-toxoid vaccine.

Authors:  B Trollfors; J Taranger; T Lagergård; L Lind; V Sundh; G Zackrisson; C U Lowe; W Blackwelder; J B Robbins
Journal:  N Engl J Med       Date:  1995-10-19       Impact factor: 91.245
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  5 in total

1.  Fusion expression and immunogenicity of Bordetella pertussis PTS1-FHA protein: implications for the vaccine development.

Authors:  Zhang Jinyong; Zhang Xiaoli; Zhang Weijun; Guo Ying; Guo Gang; Mao Xuhu; Zou Quanming
Journal:  Mol Biol Rep       Date:  2010-09-28       Impact factor: 2.316

Review 2.  Bordetella Pertussis virulence factors in the continuing evolution of whooping cough vaccines for improved performance.

Authors:  Dorji Dorji; Frits Mooi; Osvaldo Yantorno; Rajendar Deora; Ross M Graham; Trilochan K Mukkur
Journal:  Med Microbiol Immunol       Date:  2017-11-21       Impact factor: 3.402

3.  A DNA vaccine targeting the receptor-binding domain of Clostridium difficile toxin A.

Authors:  David F Gardiner; Talia Rosenberg; Jerry Zaharatos; David Franco; David D Ho
Journal:  Vaccine       Date:  2009-04-09       Impact factor: 3.641

4.  Subcutaneous Immunization with Recombinant Lactococcus lactis Expressing F1S1 Fusion Protein Induces Systemic and Mucosal Immune Responses in BALB/C Mice.

Authors:  Ali Torkashvand; Fariborz Bahrami; Minoo Adib; Soheila Ajdary
Journal:  Rep Biochem Mol Biol       Date:  2019-01

5.  Subcutaneous administration of a fusion protein composed of pertussis toxin and filamentous hemagglutinin from Bordetella pertussis induces mucosal and systemic immune responses.

Authors:  Ali Torkashvand; Fariborz Bahrami; Minoo Adib; Soheila Ajdary
Journal:  Iran J Basic Med Sci       Date:  2018-07       Impact factor: 2.699
  5 in total

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