Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Pseudomonas aeruginosa pyocyanin is critical for lung infection in mice.

Literature DB >> 15213173

Pseudomonas aeruginosa pyocyanin is critical for lung infection in mice.

Gee W Lau¹, Huimin Ran, Fansheng Kong, Daniel J Hassett, Dimitri Mavrodi.

Abstract

Pseudomonas aeruginosa secretes copious amounts of the redox-active phenazine, pyocyanin (PCN), during cystic fibrosis lung infection. PCN has been shown to interfere with a variety of cellular processes in cultured lung epithelial cells. Here, by using two respiratory tract models of infection, we demonstrate that PCN mediates tissue damage and necrosis during lung infection.

Entities: Chemical Disease Species

Mesh：

Substances：
Pyocyanine

Year: 2004 PMID： 15213173 PMCID： PMC427412 DOI： 10.1128/IAI.72.7.4275-4278.2004

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

19 in total

1. A functional genomic analysis of type 3 Streptococcus pneumoniae virulence.

Authors: G W Lau; S Haataja; M Lonetto; S E Kensit; A Marra; A P Bryant; D McDevitt; D A Morrison; D W Holden
Journal: Mol Microbiol Date: 2001-05 Impact factor: 3.501

2. Induction of neutrophil apoptosis by the Pseudomonas aeruginosa exotoxin pyocyanin: a potential mechanism of persistent infection.

Authors: Lynne R Usher; Roderick A Lawson; Ian Geary; Christopher J Taylor; Colin D Bingle; Graham W Taylor; Moira K B Whyte
Journal: J Immunol Date: 2002-02-15 Impact factor: 5.422

3. A quorum sensing-associated virulence gene of Pseudomonas aeruginosa encodes a LysR-like transcription regulator with a unique self-regulatory mechanism.

Authors: H Cao; G Krishnan; B Goumnerov; J Tsongalis; R Tompkins; L G Rahme
Journal: Proc Natl Acad Sci U S A Date: 2001-11-27 Impact factor: 11.205

4. Functional analysis of genes for biosynthesis of pyocyanin and phenazine-1-carboxamide from Pseudomonas aeruginosa PAO1.

Authors: D V Mavrodi; R F Bonsall; S M Delaney; M J Soule; G Phillips; L S Thomashow
Journal: J Bacteriol Date: 2001-11 Impact factor: 3.490

5. Use of the Galleria mellonella caterpillar as a model host to study the role of the type III secretion system in Pseudomonas aeruginosa pathogenesis.

Authors: Sachiko Miyata; Monika Casey; Dara W Frank; Frederick M Ausubel; Eliana Drenkard
Journal: Infect Immun Date: 2003-05 Impact factor: 3.441

6. Functions required for extracellular quinolone signaling by Pseudomonas aeruginosa.

Authors: Larry A Gallagher; Susan L McKnight; Marina S Kuznetsova; Everett C Pesci; Colin Manoil
Journal: J Bacteriol Date: 2002-12 Impact factor: 3.490

7. The Pseudomonas aeruginosa secretory product pyocyanin inactivates alpha1 protease inhibitor: implications for the pathogenesis of cystic fibrosis lung disease.

Authors: B E Britigan; M A Railsback; C D Cox
Journal: Infect Immun Date: 1999-03 Impact factor: 3.441

8. Pyocyanin induces oxidative stress in human endothelial cells and modulates the glutathione redox cycle.

Authors: Michael Muller
Journal: Free Radic Biol Med Date: 2002-12-01 Impact factor: 7.376

9. The Pseudomonas secretory product pyocyanin inhibits catalase activity in human lung epithelial cells.

Authors: Yunxia Q O'Malley; Krzysztof J Reszka; George T Rasmussen; Maher Y Abdalla; Gerene M Denning; Bradley E Britigan
Journal: Am J Physiol Lung Cell Mol Physiol Date: 2003-07-18 Impact factor: 5.464

10. Human targets of Pseudomonas aeruginosa pyocyanin.

Authors: Huimin Ran; Daniel J Hassett; Gee W Lau
Journal: Proc Natl Acad Sci U S A Date: 2003-11-06 Impact factor: 11.205

138 in total

1. Strain-dependent induction of neutrophil histamine production and cell death by Pseudomonas aeruginosa.

Authors: Xiang Xu; Hong Zhang; Yuanlin Song; Susan V Lynch; Clifford A Lowell; Jeanine P Wiener-Kronish; George H Caughey
Journal: J Leukoc Biol Date: 2011-11-10 Impact factor: 4.962

Review 2. Innate immune responses to Pseudomonas aeruginosa infection.

Authors: Elise G Lavoie; Tamding Wangdi; Barbara I Kazmierczak
Journal: Microbes Infect Date: 2011-08-02 Impact factor: 2.700

Review 3. Innate Immune Signaling Activated by MDR Bacteria in the Airway.

Authors: Dane Parker; Danielle Ahn; Taylor Cohen; Alice Prince
Journal: Physiol Rev Date: 2016-01 Impact factor: 37.312

4. Down regulation of virulence factors of Pseudomonas aeruginosa by salicylic acid attenuates its virulence on Arabidopsis thaliana and Caenorhabditis elegans.

Authors: B Prithiviraj; H P Bais; T Weir; B Suresh; E H Najarro; B V Dayakar; H P Schweizer; J M Vivanco
Journal: Infect Immun Date: 2005-09 Impact factor: 3.441

5. Pseudomonas Quinolone Signal Induces Oxidative Stress and Inhibits Heme Oxygenase-1 Expression in Lung Epithelial Cells.

Authors: Maher Y Abdalla; Traci Hoke; Javier Seravalli; Barbara L Switzer; Melissa Bavitz; Jill D Fliege; Peter J Murphy; Bradley E Britigan
Journal: Infect Immun Date: 2017-08-18 Impact factor: 3.441

6. The purification, crystallization and preliminary structural characterization of FAD-dependent monooxygenase PhzS, a phenazine-modifying enzyme from Pseudomonas aeruginosa.

Authors: Neelakshi Gohain; Linda S Thomashow; Dmitri V Mavrodi; Wulf Blankenfeldt
Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun Date: 2006-09-30