| Literature DB >> 1521161 |
M H Chase1, J K Engelhardt, A M Adinolfi, S S Chirwa.
Abstract
The present study was undertaken to determine the manner in which aging affects the function and structure of the masseter nerve in old cats. Electrophysiological data demonstrated a significant decrease in the conduction velocity of the action potential in old cats compared with that observed in adult cats. Light microscopic analyses revealed an age-dependent decrease in axon diameter. Electron microscopic observations of the masseter nerve in the aged cats revealed a disruption of the myelin sheaths and a pronounced increase in collagen fibers in the endoneurium and perineurium. These morphological changes are discussed and then related to the decrease in conduction velocity which was observed in the electrophysiological portion of this study.Entities:
Mesh:
Year: 1992 PMID: 1521161 DOI: 10.1016/0006-8993(92)91637-t
Source DB: PubMed Journal: Brain Res ISSN: 0006-8993 Impact factor: 3.252