Literature DB >> 1521146

Convulsive seizures in rats induced by N-methyl-D-aspartate injection into the massa intermedia.

Y Hirayasu1, J A Wada.   

Abstract

The behavioral and electroencephalographic effects of N-methyl-D-aspartate (NMDA, 25 nmol/1 microliter) injection into the massa intermedia (MI) was examined in rats. The injection caused violent running/jumping and shrill vocalization without evidence of EEG seizure in the hippocampus (HP) and amygdala (AM). Animals with the injection site located in the reuniens nucleus subsequently developed generalized tonic and then clonic seizure, leading to fatal status epilepticus in some animals. Intermittent or continuous EEG discharge in the limbic system was found during clonic seizures. These findings suggest that the NMDA receptor in the reuniens nucleus in the MI participates in the generation and expression of convulsive seizure in rats.

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Year:  1992        PMID： 1521146     DOI： 10.1016/0006-8993(92)90534-g

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  9 in total

Review 1.  The reuniens and rhomboid nuclei: neuroanatomy, electrophysiological characteristics and behavioral implications.

Authors:  Jean-Christophe Cassel; Anne Pereira de Vasconcelos; Michaël Loureiro; Thibault Cholvin; John C Dalrymple-Alford; Robert P Vertes
Journal:  Prog Neurobiol       Date:  2013-09-08       Impact factor: 11.685

2.  Nucleus reuniens thalami modulates activity in hippocampal field CA1 through excitatory and inhibitory mechanisms.

Authors:  M J Dolleman-Van der Weel; F H Lopes da Silva; M P Witter
Journal:  J Neurosci       Date:  1997-07-15       Impact factor: 6.167

3.  Chemogenetic silencing of the midline and intralaminar thalamus blocks amygdala-kindled seizures.

Authors:  Evan Wicker; Patrick A Forcelli
Journal:  Exp Neurol       Date:  2016-07-09       Impact factor: 5.330

4.  Prevalence and anatomical characteristics of the human massa intermedia.

Authors:  Alireza Borghei; Ali Piracha; Sepehr Sani
Journal:  Brain Struct Funct       Date:  2021-01-01       Impact factor: 3.270

5.  Relationship among interthalamic adhesion size, thalamic anatomy and neuropsychological functions in healthy volunteers.

Authors:  Nishad R Damle; Toshikazu Ikuta; Majnu John; Bart D Peters; Pamela DeRosse; Anil K Malhotra; Philip R Szeszko
Journal:  Brain Struct Funct       Date:  2016-11-19       Impact factor: 3.270

6.  Thalamic Massa Intermedia in Children with and without Midline Brain Malformations.

Authors:  M T Whitehead; N Najim
Journal:  AJNR Am J Neuroradiol       Date:  2020-02-27       Impact factor: 3.825

Review 7.  The nucleus reuniens of the thalamus sits at the nexus of a hippocampus and medial prefrontal cortex circuit enabling memory and behavior.

Authors:  Margriet J Dolleman-van der Weel; Amy L Griffin; Hiroshi T Ito; Matthew L Shapiro; Menno P Witter; Robert P Vertes; Timothy A Allen
Journal:  Learn Mem       Date:  2019-06-17       Impact factor: 2.460

8.  Glioma consensus contouring recommendations from a MR-Linac International Consortium Research Group and evaluation of a CT-MRI and MRI-only workflow.

Authors:  Chia-Lin Tseng; James Stewart; Gillian Whitfield; Joost J C Verhoeff; Joseph Bovi; Hany Soliman; Caroline Chung; Sten Myrehaug; Mikki Campbell; Eshetu G Atenafu; Chinthaka Heyn; Sunit Das; James Perry; Mark Ruschin; Arjun Sahgal
Journal:  J Neurooncol       Date:  2020-08-29       Impact factor: 4.130

9.  Structural connectivity of the human massa intermedia: A probabilistic tractography study.

Authors:  Alireza Borghei; Irem Kapucu; Robert Dawe; Mehmet Kocak; Sepehr Sani
Journal:  Hum Brain Mapp       Date:  2021-01-20       Impact factor: 5.038
  9 in total

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