Literature DB >> 15210147

Synthesis and antimicrobial activity of erythromycin-A oxime analogs.

Deepa Pandey1, S B Katti, W Haq, C K M Tripathi.   

Abstract

A series of erythromycin-A oxime ether as well as esters have been synthesized. Ether derivatives were synthesized through the epoxy ether intermediate of erythromycin-9-oxime, followed by opening of the epoxy linkage through various amines, whereas esters have been prepared through DCC mediated protocol. These derivatives have been evaluated for antibacterial activity and found to be as active as erythromycin-A.

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Year:  2004        PMID: 15210147     DOI: 10.1016/j.bmc.2004.05.011

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN: 0968-0896            Impact factor:   3.641


  1 in total

1.  Synthesis of Hydrophilic Aminooxy Linkers and Multivalent Cores for Chemoselective Aldehyde/Ketone Conjugation.

Authors:  Katherine D McReynolds; Dustin Dimas; Hoang Le
Journal:  Tetrahedron Lett       Date:  2014-04-02       Impact factor: 2.415

  1 in total

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