Literature DB >> 15209157

Bioactive peptides based on diversity libraries, supramolecular chemistry and rational design: a new class of peptide drugs. Introduction.

Rob Meloen1, Peter Timmerman, Hans Langedijk.   

Abstract

A new class of pharmaceutical molecules--synthetic vaccines, synthetic diagnostics and peptide drugs--are emerging based on recent advances of peptide libraries, supramolecular chemistry and rational design. The molecules of this growing class have exciting potential, not met by classical drugs based on small molecules or recombinant proteins.

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Year:  2004        PMID: 15209157     DOI: 10.1023/b:modi.0000025698.16766.11

Source DB:  PubMed          Journal:  Mol Divers        ISSN: 1381-1991            Impact factor:   2.943


  18 in total

1.  Selection and characterization of a new class of peptide exosite inhibitors of coagulation factor VIIa.

Authors:  M S Dennis; M Roberge; C Quan; R A Lazarus
Journal:  Biochemistry       Date:  2001-08-14       Impact factor: 3.162

2.  Inhibition of hepatitis C virus NS3 protease by peptides derived from complementarity-determining regions (CDRs) of the monoclonal antibody 8D4: tolerance of a CDR peptide to conformational changes of a target.

Authors:  Kouhei Tsumoto; Satoru Misawa; Yoichi Ohba; Takamasa Ueno; Hideya Hayashi; Nobuhiro Kasai; Hideki Watanabe; Ryutaro Asano; Izumi Kumagai
Journal:  FEBS Lett       Date:  2002-08-14       Impact factor: 4.124

3.  Structural determinants of the calpain inhibitory activity of calpastatin peptide B27-WT.

Authors:  Russell Betts; Shantel Weinsheimer; Grant E Blouse; John Anagli
Journal:  J Biol Chem       Date:  2002-12-24       Impact factor: 5.157

4.  Hormone mimicry.

Authors:  J A Wells
Journal:  Science       Date:  1996-07-26       Impact factor: 47.728

5.  Structure-based design and characterization of exocyclic peptidomimetics that inhibit TNF alpha binding to its receptor.

Authors:  W Takasaki; Y Kajino; K Kajino; R Murali; M I Greene
Journal:  Nat Biotechnol       Date:  1997-11       Impact factor: 54.908

6.  A cyclic pentapeptide derived from the second EGF-like domain of Factor VII is an inhibitor of tissue factor dependent coagulation and thrombus formation.

Authors:  Lars Orning; Peter M Fischer; Chih-Kao Hu; Erik Agner; May Engebretsen; Mette Husbyn; Lizette B Petersen; Una Orvim; Miguel Llinas; Kjell S Sakariassen
Journal:  Thromb Haemost       Date:  2002-01       Impact factor: 5.249

7.  Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine.

Authors:  S E Cwirla; P Balasubramanian; D J Duffin; C R Wagstrom; C M Gates; S C Singer; A M Davis; R L Tansik; L C Mattheakis; C M Boytos; P J Schatz; D P Baccanari; N C Wrighton; R W Barrett; W J Dower
Journal:  Science       Date:  1997-06-13       Impact factor: 47.728

8.  Inhibition of septic shock in mice by an oligopeptide from the beta-chain of human chorionic gonadotrophin hormone.

Authors:  Nisar A Khan; Afshan Khan; Huub F J Savelkoul; Robbert Benner
Journal:  Hum Immunol       Date:  2002-01       Impact factor: 2.850

9.  Pharmacological profiles of peptide drug candidates for the treatment of Alzheimer's disease.

Authors:  Céline Adessi; Marie-José Frossard; Christophe Boissard; Santiago Fraga; Sylvain Bieler; Thomas Ruckle; Francis Vilbois; Sandra M Robinson; Manfred Mutter; William A Banks; Claudio Soto
Journal:  J Biol Chem       Date:  2003-02-10       Impact factor: 5.157

Review 10.  Structure-based design of mimetics for granulocyte-macrophage colony stimulating factor (GM-CSF).

Authors:  Cristina Monfardini; Gabriela Canziani; Carmela Plugariu; Thomas Kieber-Emmons; A Paul Godillot; Joann Kwah; Joanna Bajgier; Irwin Chaiken; William V Williams
Journal:  Curr Pharm Des       Date:  2002       Impact factor: 3.116

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  3 in total

1.  In silico study of peptide inhibitors against BACE 1.

Authors:  Navya Raj; Agnes Helen; N Manoj; G Harish; Vipin Thomas; Shailja Singh; Seema Sehrawat; Shaguna Seth; Achuthsankar S Nair; Abhinav Grover; Pawan K Dhar
Journal:  Syst Synth Biol       Date:  2015-03-19

2.  Rapid probing of biological surfaces with a sparse-matrix peptide library.

Authors:  Daniel K Yarbrough; Randal Eckert; Jian He; Elizabeth Hagerman; Fengxia Qi; Renate Lux; Ben Wu; Maxwell H Anderson; Wenyuan Shi
Journal:  PLoS One       Date:  2011-08-15       Impact factor: 3.240

3.  Peptide Inhibition of Topoisomerase IB from Plasmodium falciparum.

Authors:  Amit Roy; Ilda D'Annessa; Christine J F Nielsen; David Tordrup; Rune R Laursen; Birgitta Ruth Knudsen; Alessandro Desideri; Felicie Faucon Andersen
Journal:  Mol Biol Int       Date:  2011-05-04
  3 in total

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