Literature DB >> 15206776

Strategies leading to MT2 selective melatonin receptor antagonists.

Gilberto Spadoni1, Annalida Bedini, Giovanni Piersanti, Marco Mor, Silvia Rivara, Giorgio Tarzia.   

Abstract

Studies of the physiological actions of melatonin have been hindered by the lack of specific, potent and subtype selective agonists and antagonists. This paper reviews our progress in developing subtype selective melatonin antagonists. Evidence is presented suggesting the structural features conferring MT2 selective antagonism.

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Year:  2003        PMID: 15206776     DOI: 10.1007/978-1-4615-0135-0_66

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  1 in total

1.  New MT₂ Melatonin Receptor-Selective Ligands: Agonists and Partial Agonists.

Authors:  Jean A Boutin; Anne Bonnaud; Chantal Brasseur; Olivier Bruno; Nolwenn Lepretre; Peter Oosting; Sophie Coumailleau; Philippe Delagrange; Olivier Nosjean; Céline Legros
Journal:  Int J Mol Sci       Date:  2017-06-23       Impact factor: 5.923

  1 in total

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