Literature DB >> 15205448

The ponA gene of Enterococcus faecalis JH2-2 codes for a low-affinity class A penicillin-binding protein.

Colette Duez1, Séverine Hallut, Noureddine Rhazi, Séverine Hubert, Ana Amoroso, Fabrice Bouillenne, André Piette, Jacques Coyette.   

Abstract

A soluble derivative of the Enterococcus faecalis JH2-2 class A PBP1 (*PBP1) was overproduced and purified. It exhibited a glycosyltransferase activity on the Escherichia coli 14C-labeled lipid II precursor. As a DD- peptidase, it could hydrolyze thiolester substrates with efficiencies similar to those of other class A penicillin-binding proteins (PBPs) and bind beta-lactams, but with k2/K (a parameter accounting for the acylation step efficiency) values characteristic of penicillin-resistant PBPs.

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Year:  2004        PMID： 15205448      PMCID： PMC421628          DOI： 10.1128/JB.186.13.4412-4416.2004

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  42 in total

1.  Functional characterization of penicillin-binding protein 1b from Streptococcus pneumoniae.

Authors:  Anne Marie Di Guilmi; Andréa Dessen; Otto Dideberg; Thierry Vernet
Journal:  J Bacteriol       Date:  2003-03       Impact factor: 3.490

Review 2.  Biochemistry and comparative genomics of SxxK superfamily acyltransferases offer a clue to the mycobacterial paradox: presence of penicillin-susceptible target proteins versus lack of efficiency of penicillin as therapeutic agent.

Authors:  Colette Goffin; Jean-Marie Ghuysen
Journal:  Microbiol Mol Biol Rev       Date:  2002-12       Impact factor: 11.056

3.  Peptidoglycan synthesis in the absence of class A penicillin-binding proteins in Bacillus subtilis.

Authors:  Derrell C McPherson; David L Popham
Journal:  J Bacteriol       Date:  2003-02       Impact factor: 3.490

4.  The catalytic, glycosyl transferase and acyl transferase modules of the cell wall peptidoglycan-polymerizing penicillin-binding protein 1b of Escherichia coli.

Authors:  M Terrak; T K Ghosh; J van Heijenoort; J Van Beeumen; M Lampilas; J Aszodi; J A Ayala; J M Ghuysen; M Nguyen-Distèche
Journal:  Mol Microbiol       Date:  1999-10       Impact factor: 3.501

5.  The penicillin resistance of Enterococcus faecalis JH2-2r results from an overproduction of the low-affinity penicillin-binding protein PBP4 and does not involve a psr-like gene.

Authors:  Colette Duez; Willy Zorzi; Frédéric Sapunaric; Ana Amoroso; Iris Thamm; Jacques Coyette
Journal:  Microbiology (Reading)       Date:  2001-09       Impact factor: 2.777

6.  PrfA protein of Bacillus species: prediction and demonstration of endonuclease activity on DNA.

Authors:  Daniel J Rigden; Peter Setlow; Barbara Setlow; Irina Bagyan; Richard A Stein; Mark J Jedrzejas
Journal:  Protein Sci       Date:  2002-10       Impact factor: 6.725

7.  The glycosyltransferase domain of penicillin-binding protein 2a from Streptococcus pneumoniae catalyzes the polymerization of murein glycan chains.

Authors:  Anne Marie Di Guilmi; Andréa Dessen; Otto Dideberg; Thierry Vernet
Journal:  J Bacteriol       Date:  2003-08       Impact factor: 3.490

8.  Role of class A penicillin-binding proteins in PBP5-mediated beta-lactam resistance in Enterococcus faecalis.

Authors:  Ana Arbeloa; Heidi Segal; Jean-Emmanuel Hugonnet; Nathalie Josseaume; Lionnel Dubost; Jean-Paul Brouard; Laurent Gutmann; Dominique Mengin-Lecreulx; Michel Arthur
Journal:  J Bacteriol       Date:  2004-03       Impact factor: 3.490

9.  Fluorescence and circular dichroism studies on the Streptomyces R61 DD-carboxypeptidase-transpeptidase. Penicillin binding by the enzyme.

Authors:  M Nieto; H R Perkins; J M Frère; J M Ghuysen
Journal:  Biochem J       Date:  1973-11       Impact factor: 3.857

10.  Conjugal transfer of plasmid-borne multiple antibiotic resistance in Streptococcus faecalis var. zymogenes.

Authors:  A E Jacob; S J Hobbs
Journal:  J Bacteriol       Date:  1974-02       Impact factor: 3.490
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  7 in total

1.  Contribution of penicillin-binding protein homologs to antibiotic resistance, cell morphology, and virulence of Listeria monocytogenes EGDe.

Authors:  Caitriona M Guinane; Paul D Cotter; R Paul Ross; Colin Hill
Journal:  Antimicrob Agents Chemother       Date:  2006-08       Impact factor: 5.191

2.  Penicillin-binding protein 1a promotes resistance of group B streptococcus to antimicrobial peptides.

Authors:  Andrea Hamilton; David L Popham; David J Carl; Xavier Lauth; Victor Nizet; Amanda L Jones
Journal:  Infect Immun       Date:  2006-11       Impact factor: 3.441

3.  Role of Toll-like receptor 2 in innate resistance to Group B Streptococcus.

Authors:  Iain R Asplin; David J Carl; Sing Sing Way; Amanda L Jones
Journal:  Microb Pathog       Date:  2007-08-10       Impact factor: 3.738

4.  Multiple Low-Reactivity Class B Penicillin-Binding Proteins Are Required for Cephalosporin Resistance in Enterococci.

Authors:  Dušanka Djorić; Jaime L Little; Christopher J Kristich
Journal:  Antimicrob Agents Chemother       Date:  2020-03-24       Impact factor: 5.191

Review 5.  Mechanisms of antibiotic resistance in enterococci.

Authors:  William R Miller; Jose M Munita; Cesar A Arias
Journal:  Expert Rev Anti Infect Ther       Date:  2014-10       Impact factor: 5.091

6.  AmpC β-Lactamase Variable Expression in Common Multidrug-Resistant Nosocomial Bacterial Pathogens from a Tertiary Hospital in Cairo, Egypt.

Authors:  Aliaa Ali El Shamy; Zainab Zakaria; Mahmoud M Tolba; Nermeen Salah Eldin; Al-Taher Rabea; Mahmoud M Tawfick; Hebatallah A Nasser
Journal:  Int J Microbiol       Date:  2021-03-28

7.  Antimicrobial resistance, virulence genes and biofilm formation in Enterococcus species isolated from milk of sheep and goat with subclinical mastitis.

Authors:  Mona A El-Zamkan; Hams M A Mohamed
Journal:  PLoS One       Date:  2021-11-15       Impact factor: 3.240
  7 in total

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