AIM: The study examined whether associations between bone, body composition and strength are age dependent. SUBJECTS AND METHODS: Two age levels (premenarcheal girls and postmenopausal women on HRT) were studied in a 10-month follow-up. Bone, lean and fat mass were measured by dual-energy X-ray absorptiometry (DXA), and strength was measured using an isokinetic dynamometer. RESULTS: In girls, significant correlations were found between mass (lean, fat and body mass), strength and most bone characteristics (r = 0.15-0.93). At the proximal femur changes in bone mineral density (BMD) were moderately related to changes in body composition. In the women, body mass and lean mass were significantly correlated with most bone characteristics (r = 0.34-0.82). Low to moderate correlations were observed between changes in bone and changes in body composition. After controlling for lean mass the relation between strength and bone was no longer significant. CONCLUSIONS: In premenarcheal girls, bone is partly determined by mass, with lean mass the most important predictor at the femoral sites. In postmenopausal women, lean mass is an important determinant of bone mineral content (BMC) and BMD, but changes in BMD are related to changes in fat. The relation between strength and BMD is mainly attributable to the relation between lean mass and BMD. The contributory effects of soft tissue to bone change over different life periods.
AIM: The study examined whether associations between bone, body composition and strength are age dependent. SUBJECTS AND METHODS: Two age levels (premenarcheal girls and postmenopausal women on HRT) were studied in a 10-month follow-up. Bone, lean and fat mass were measured by dual-energy X-ray absorptiometry (DXA), and strength was measured using an isokinetic dynamometer. RESULTS: In girls, significant correlations were found between mass (lean, fat and body mass), strength and most bone characteristics (r = 0.15-0.93). At the proximal femur changes in bone mineral density (BMD) were moderately related to changes in body composition. In the women, body mass and lean mass were significantly correlated with most bone characteristics (r = 0.34-0.82). Low to moderate correlations were observed between changes in bone and changes in body composition. After controlling for lean mass the relation between strength and bone was no longer significant. CONCLUSIONS: In premenarcheal girls, bone is partly determined by mass, with lean mass the most important predictor at the femoral sites. In postmenopausal women, lean mass is an important determinant of bone mineral content (BMC) and BMD, but changes in BMD are related to changes in fat. The relation between strength and BMD is mainly attributable to the relation between lean mass and BMD. The contributory effects of soft tissue to bone change over different life periods.
Authors: Michael T C Liang; Stanley Bassin; Darren Dutto; William Braun; Nathan Wong; Andria M Pontello; Dan M Cooper; Sara B Arnaud Journal: J Clin Densitom Date: 2007-03-07 Impact factor: 2.617
Authors: L A Milliken; E Cussler; R A Zeller; J-E Choi; L Metcalfe; S B Going; T G Lohman Journal: Osteoporos Int Date: 2008-07-08 Impact factor: 4.507
Authors: Jordan J Smith; Narelle Eather; Philip J Morgan; Ronald C Plotnikoff; Avery D Faigenbaum; David R Lubans Journal: Sports Med Date: 2014-09 Impact factor: 11.136
Authors: Jorge Perez-Gomez; German Vicente Rodriguez; Ignacio Ara; Hugo Olmedillas; Javier Chavarren; Juan Jose González-Henriquez; Cecilia Dorado; José A L Calbet Journal: Eur J Appl Physiol Date: 2007-12-15 Impact factor: 3.078