Literature DB >> 15203567

Elevated plasma phospholipase A2 and platelet-activating factor acetylhydrolase activity in colorectal cancer.

Yves Denizot1, Véronique Truffinet, Stéphane Bouvier, Alain Gainant, Pierre Cubertafond, Muriel Mathonnet.   

Abstract

This clinical study reports that blood levels of the pro-inflammatory mediator platelet-activating factor (PAF) did not change in colorectal cancer patients. In contrast, plasma levels of two enzymatic activities, one implicated in PAF production (i.e. phospholipase A2) and one in PAF degradation (i.e. PAF acetylhydrolase activity) were significantly elevated.

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Year:  2004        PMID： 15203567      PMCID： PMC1781534          DOI： 10.1080/09629350410001664824

Source DB:  PubMed          Journal:  Mediators Inflamm        ISSN： 0962-9351            Impact factor:   4.711


  4 in total

1.  Tissue concentrations of platelet-activating factor in colorectal carcinoma: inverse relationships with Dukes' stage of patients.

Authors:  Yves Denizot; Alain Gainant; Laurence Guglielmi; Stephane Bouvier; Pierre Cubertafond; Murielle Mathonnet
Journal:  Oncogene       Date:  2003-10-16       Impact factor: 9.867

Review 2.  Serum phospholipases A2 in inflammatory diseases.

Authors:  T J Nevalainen
Journal:  Clin Chem       Date:  1993-12       Impact factor: 8.327

3.  Potential angiogenic role of platelet-activating factor in human breast cancer.

Authors:  G Montrucchio; A Sapino; B Bussolati; G Ghisolfi; S Rizea-Savu; L Silvestro; E Lupia; G Camussi
Journal:  Am J Pathol       Date:  1998-11       Impact factor: 4.307

4.  Elevation of serum group II phospholipase A2 in patients with cancers of digestive organs.

Authors:  M Ogawa; S Yamashita; K Sakamoto; S Ikei
Journal:  Res Commun Chem Pathol Pharmacol       Date:  1991-11
  4 in total
  6 in total

Review 1.  The Potential Role of Dietary Platelet-Activating Factor Inhibitors in Cancer Prevention and Treatment.

Authors:  Ronan Lordan; Alexandros Tsoupras; Ioannis Zabetakis
Journal:  Adv Nutr       Date:  2019-01-01       Impact factor: 8.701

2.  Molecular basis of phospholipase A2 activity toward phospholipids with sn-1 substitutions.

Authors:  Lars Linderoth; Thomas L Andresen; Kent Jørgensen; Robert Madsen; Günther H Peters
Journal:  Biophys J       Date:  2007-09-07       Impact factor: 4.033

3.  Deficiency of phospholipase A2 group 7 decreases intestinal polyposis and colon tumorigenesis in Apc(Min/+) mice.

Authors:  Changxin Xu; Ethan C Reichert; Tomoyuki Nakano; Mariah Lohse; Alison A Gardner; Mónica P Revelo; Matthew K Topham; Diana M Stafforini
Journal:  Cancer Res       Date:  2013-01-29       Impact factor: 12.701

Review 4.  Forty Years Since the Structural Elucidation of Platelet-Activating Factor (PAF): Historical, Current, and Future Research Perspectives.

Authors:  Ronan Lordan; Alexandros Tsoupras; Ioannis Zabetakis; Constantinos A Demopoulos
Journal:  Molecules       Date:  2019-12-03       Impact factor: 4.411

5.  Elevated mean platelet volume predicts poor prognosis in colorectal cancer.

Authors:  Na Li; Zhiwei Yu; Xin Zhang; Tiemin Liu; Yu-Xiang Sun; Rui-Tao Wang; Kai-Jiang Yu
Journal:  Sci Rep       Date:  2017-08-31       Impact factor: 4.379

6.  Economical and easily detectable markers of digestive tumors: platelet parameters.

Authors:  Yingying Chen; Wei Yang; Lifang Ye; Suzhen Lin; Kuangyi Shu; Xiao Yang; Xinyi Ai; Yating Yao; Minghua Jiang
Journal:  Biomark Med       Date:  2021-01-21       Impact factor: 2.851
  6 in total

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