Literature DB >> 15203294

Comparison of characteristics between geriatric and younger subjects with schizophrenia in community.

Mao-Sheng Ran1, Meng-Ze Xiang, Yeates Conwell, J Steven Lamberti, Ming-Sheng Huang, You-He Shan, Xian-Zhang Hu.   

Abstract

Relatively little is known about the different characteristics of non-institutionalized geriatric and younger subjects with schizophrenia. This study compared demographic and clinical characteristics of all the geriatric, middle-age and young subjects with schizophrenia living in a Chinese rural community. Geriatric (age >/= 65 years) (N = 51), middle-age (age 41-64 years) (N = 263) and young subjects with schizophrenia (age 15-40 years) (N = 196) in a rural community were assessed with the Present State Examination and Social Disability Screening Schedule. Age at first onset was significantly older in geriatric male and female groups. While there were no significant differences of negative symptoms among the three groups, the rates of lifetime nuclear syndrome were significantly lower in geriatric subjects compared to the other two groups. Geriatric subjects were less likely to have been hospitalized (9.8%) than middle-age (19.0%) and younger subjects (24.8%). Although the duration of illness was significantly longer in geriatric subjects than in the other two groups, the clinical outcome was significantly better in the geriatric group and social functioning scores were similar among the three groups. Geriatric subjects were more likely to be female, with longer duration of illness, fewer "core" symptoms, relatively stable social functioning and clinical outcome. The pathogenesis and psychopathology of geriatric subjects may be different compared to younger subjects with schizophrenia.

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Year:  2004        PMID: 15203294     DOI: 10.1016/j.jpsychires.2003.12.003

Source DB:  PubMed          Journal:  J Psychiatr Res        ISSN: 0022-3956            Impact factor:   4.791


  4 in total

1.  Schizophrenia--a predictor of suicide during the second half of life?

Authors:  Annette Erlangsen; William W Eaton; Preben Bo Mortensen; Yeates Conwell
Journal:  Schizophr Res       Date:  2011-10-22       Impact factor: 4.939

2.  Differences in mortality and suicidal behaviour between treated and never-treated people with schizophrenia in rural China.

Authors:  Mao-Sheng Ran; Cecilia Lai-Wan Chan; Eric Yu-Hai Chen; Wen-Jun Mao; Shi-Hui Hu; Cui-Ping Tang; Fu-Rong Lin; Yeates Conwell
Journal:  Br J Psychiatry       Date:  2009-08       Impact factor: 9.319

3.  Serum BDNF Is Positively Associated With Negative Symptoms in Older Adults With Schizophrenia.

Authors:  Sasha S Binford; Erin M Hubbard; Elena Flowers; Bruce L Miller; Heather Leutwyler
Journal:  Biol Res Nurs       Date:  2017-10-19       Impact factor: 2.522

4.  Changes in treatment status of patients with severe mental illness in rural China, 1994-2015.

Authors:  Mao-Sheng Ran; Xue Weng; Yu-Jun Liu; Tian-Ming Zhang; Yue-Hui Yu; Man-Man Peng; Wei Luo; Shi-Hui Hu; Xin Yang; Bo Liu; Tin Zhang; Graham Thornicroft; Cecilia Lai-Wan Chan; Meng-Ze Xiang
Journal:  BJPsych Open       Date:  2019-03
  4 in total

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