Literature DB >> 15202913

A new route to aristocularine alkaloids: total synthesis of aristoyagonine.

Anne Moreau1, Axel Couture, Eric Deniau, Pierre Grandclaudon.   

Abstract

A short and efficient synthesis of aristocularines, involving the sequential construction of phosphorylated 4-alkoxyisoindolinones, Horner-type reaction, and ultimate cyclization by diaryl ether coupling, is disclosed. The success of this new conceptual approach is demonstrated by the total synthesis of the aristocularine alkaloid aristoyagonine.

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Year:  2004        PMID: 15202913     DOI: 10.1021/jo049869g

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  4 in total

1.  Total Synthesis of Oxepin and Dihydrooxepin Containing Natural Products.

Authors:  Kevin Rafael Sokol; Thomas Magauer
Journal:  Synthesis (Stuttg)       Date:  2021-06-24       Impact factor: 3.157

2.  Synthesis of 3-Alkylideneisoindolin-1-ones via Sonogashira Cyclocarbonylative Reactions of 2-Ethynylbenzamides.

Authors:  Gianluigi Albano; Stefano Giuntini; Laura Antonella Aronica
Journal:  J Org Chem       Date:  2020-07-14       Impact factor: 4.354

Review 3.  The chemistry of isoindole natural products.

Authors:  Klaus Speck; Thomas Magauer
Journal:  Beilstein J Org Chem       Date:  2013-10-10       Impact factor: 2.883

4.  Efficient synthesis of a (Z)-3-methyleneisoindolin-1-one library using Cu(OAc)₂•H₂O/DBU under microwave irradiation.

Authors:  Li Zhang; Yongliang Zhang; Xin Wang; Jingkang Shen
Journal:  Molecules       Date:  2013-01-04       Impact factor: 4.411

  4 in total

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