Literature DB >> 15202731

Talniflumate (Genaera).

Darryl Knight1.   

Abstract

Talniflumate, an anti-inflammatory molecule that was originally developed by Laboratorios Bago, is currently being developed by Genaera as a mucoregulator for the treatment of cystic fibrosis, chronic obstructive pulmonary disease and asthma. Phase I trials with talniflumate had been completed by August 2001, and phase II trials were underway in Ireland for the treatment of cystic fibrosis.

Entities:  

Mesh：

Substances：

Year:  2004        PMID： 15202731

Source DB:  PubMed          Journal:  Curr Opin Investig Drugs        ISSN： 1472-4472


  6 in total

Review 1.  The role of CLCA proteins in inflammatory airway disease.

Authors:  Anand C Patel; Tom J Brett; Michael J Holtzman
Journal:  Annu Rev Physiol       Date:  2009       Impact factor: 19.318

2.  Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction.

Authors:  Fen Huang; Hongkang Zhang; Meng Wu; Huanghe Yang; Makoto Kudo; Christian J Peters; Prescott G Woodruff; Owen D Solberg; Matthew L Donne; Xiaozhu Huang; Dean Sheppard; John V Fahy; Paul J Wolters; Brigid L M Hogan; Walter E Finkbeiner; Min Li; Yuh-Nung Jan; Lily Yeh Jan; Jason R Rock
Journal:  Proc Natl Acad Sci U S A       Date:  2012-09-17       Impact factor: 11.205

3.  Catalytic asymmetric acetalization of carboxylic acids for access to chiral phthalidyl ester prodrugs.

Authors:  Yingguo Liu; Qiao Chen; Chengli Mou; Lutai Pan; Xiaoyong Duan; Xingkuan Chen; Hongzhong Chen; Yanli Zhao; Yunpeng Lu; Zhichao Jin; Yonggui Robin Chi
Journal:  Nat Commun       Date:  2019-04-11       Impact factor: 14.919

4.  Cu(I)- and Pd(0)-Catalyzed Arylation of Oxadiamines with Fluorinated Halogenobenzenes: Comparison of Efficiency.

Authors:  Maria S Lyakhovich; Alexei D Averin; Olga K Grigorova; Vitaly A Roznyatovsky; Olga A Maloshitskaya; Irina P Beletskaya
Journal:  Molecules       Date:  2020-02-28       Impact factor: 4.411

Review 5.  Treating COPD with PDE 4 inhibitors.

Authors:  William M Brown
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2007

6.  Screening study for genetic polymorphisms affecting pharmacokinetics of talniflumate.

Authors:  Li Hua Jin; Bo-Hyung Kim; Ji Hyun Lee; Kidong Lee; KyuBum Kwack; Sung-Vin Yim
Journal:  Transl Clin Pharmacol       Date:  2017-12-20
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.