Literature DB >> 15201456

The CGG repeat and the FMR1 gene.

Violeta Stoyanova1, Ben A Oostra.   

Abstract

This review intends to provide the different DNA methods for diagnosis of the repeat in the FMR1 gene. The two DNA methods to determine the CGG repeat size are Southern blot hybridization and the polymerase chain reaction (PCR), including bisulfite treatment.

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Year:  2004        PMID： 15201456     DOI： 10.1385/1-59259-804-8:173

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  4 in total

1.  Elevated Fmr1 mRNA levels and reduced protein expression in a mouse model with an unmethylated Fragile X full mutation.

Authors:  J R Brouwer; E J Mientjes; C E Bakker; I M Nieuwenhuizen; L A Severijnen; H C Van der Linde; D L Nelson; B A Oostra; R Willemsen
Journal:  Exp Cell Res       Date:  2006-10-13       Impact factor: 3.905

2.  Ectopic expression of CGG containing mRNA is neurotoxic in mammals.

Authors:  Vera Hashem; Jocelyn N Galloway; Mayra Mori; Rob Willemsen; Ben A Oostra; Richard Paylor; David L Nelson
Journal:  Hum Mol Genet       Date:  2009-04-18       Impact factor: 6.150

3.  FMR1 expression in human granulosa cells increases with exon 1 CGG repeat length depending on ovarian reserve.

Authors:  Julia Rehnitz; Diego D Alcoba; Ilma S Brum; Jens E Dietrich; Berthe Youness; Katrin Hinderhofer; Birgitta Messmer; Alexander Freis; Thomas Strowitzki; Ariane Germeyer
Journal:  Reprod Biol Endocrinol       Date:  2018-07-07       Impact factor: 5.211

4.  Expression of FMRpolyG in Peripheral Blood Mononuclear Cells of Women with Fragile X Mental Retardation 1 Gene Premutation.

Authors:  Xuan Phuoc Nguyen; Adriana Vilkaite; Birgitta Messmer; Jens E Dietrich; Katrin Hinderhofer; Knut Schäkel; Thomas Strowitzki; Julia Rehnitz
Journal:  Genes (Basel)       Date:  2022-03-01       Impact factor: 4.096
  4 in total

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