The 'fixed performance' venturi: effect of downstream pressure on outflow and FIO2.

Fixed performance venturi devices should provide a predetermined oxygen concentration at an outflow which exceeds an adult's peak resting inspiratory flow rate (approximately 30 l.min(-1)). Campbell's original description mentioned the sensitivity of the venturi device to downstream resistance but gave no further details. This study examined outflow and oxygen concentration from the five standard venturi devices (24-60% O(2)) when downstream pressure increased. Outflow was exquisitely sensitive to small increases in pressure. The outflow at zero downstream pressure for the 24-40% O(2) venturi devices ranged from 40 to 50 l.min(-1) but only 2-3 mmH(2)O was needed to halve this flow and increase oxygen concentration. The 60% O(2) venturi delivered a maximum of only 30 l.min(-1) at zero downstream pressure and flow was reduced further by increasing this pressure. An increase in downstream pressure of only a few mmH(2)O increased oxygen concentration and decreased outflow of all the venturi devices tested, in most to less than normal peak tidal flow in adults.