Literature DB >> 15200340

Diastereoselective zinc-catalyzed conjugate addition of alkynes.

Thomas F Knöpfel1, Dean Boyall, Erick M Carreira.   

Abstract

[reaction: see text] The conjugate addition of in situ generated zinc alkynylides is reported. The use of chiral, ephedrine derived acceptors provides access to enantiomerically enriched beta-alkynyl acids in good yields.

Entities:  

Year:  2004        PMID： 15200340     DOI： 10.1021/ol0491585

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  A concise synthetic route to the stereotetrad core of the briarane diterpenoids.

Authors:  Nicholas G Moon; Andrew M Harned
Journal:  Org Lett       Date:  2015-04-14       Impact factor: 6.005

2.  Cu(II)-catalyzed aerobic hydroperoxidation of Meldrum's acid derivatives and application in intramolecular oxidation: a conceptual blueprint for O2/H2 dihydroxylation.

Authors:  Scott W Krabbe; Dung T Do; Jeffrey S Johnson
Journal:  Org Lett       Date:  2012-11-19       Impact factor: 6.005

3.  Development of Zn-ProPhenol-catalyzed asymmetric alkyne addition: synthesis of chiral propargylic alcohols.

Authors:  Barry M Trost; Mark J Bartlett; Andrew H Weiss; Axel Jacobi von Wangelin; Vincent S Chan
Journal:  Chemistry       Date:  2012-10-23       Impact factor: 5.236
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.