OBJECTIVE: To highlight the in vivo protein markers in human peritoneal mesothelial cells according to their anatomical distribution and their interest in theories of peritoneal repair. DESIGN: Clinical laboratory study. SETTING: University Hospital, France. PATIENTS: Sampling of mesothelial cells during 8 laparotomies by impression smears. MAIN OUTCOME MEASURES: Immunochemical semiquantitative measures of proteins. RESULTS: There were uniform ratios of protein markers among the whole peritoneal mesothelial cell population, whatever their anatomical origin (liver, stomach, omentum, small bowel, and abdominal wall). CONCLUSION: This is consistent with the surrounding uninjured mesothelial cells or the exfoliated mesothelial cells, or both, having a role in postoperative peritoneal mesothelial repair.
OBJECTIVE: To highlight the in vivo protein markers in human peritoneal mesothelial cells according to their anatomical distribution and their interest in theories of peritoneal repair. DESIGN: Clinical laboratory study. SETTING: University Hospital, France. PATIENTS: Sampling of mesothelial cells during 8 laparotomies by impression smears. MAIN OUTCOME MEASURES: Immunochemical semiquantitative measures of proteins. RESULTS: There were uniform ratios of protein markers among the whole peritoneal mesothelial cell population, whatever their anatomical origin (liver, stomach, omentum, small bowel, and abdominal wall). CONCLUSION: This is consistent with the surrounding uninjured mesothelial cells or the exfoliated mesothelial cells, or both, having a role in postoperative peritoneal mesothelial repair.
Authors: Peter Falk; Fernando Ruiz-Jasbon; Karin Strigård; Ulf Gunnarsson; Marie-Lois Ivarsson Journal: Biol Open Date: 2017-09-15 Impact factor: 2.422