Literature DB >> 15198192

A case of legionellosis during treatment with a TNFalpha antagonist.

Marielle J Wondergem1, Alexandre E Voskuyl, Michiel A van Agtmael.   

Abstract

We report a patient with Legionella pneumophila pneumonia after infliximab therapy for rheumatoid arthritis. Arguments are discussed for an emerging incidence of infections with intracellular microorganisms, granulomatous and non-granulomatous, in patients having received anti-TNFalpha therapy. These discussions consist of clinical and epidemiological data, experimental data in animals, theoretical evidence, and we provide a possible pathogenetic mechanism.

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Year:  2004        PMID: 15198192     DOI: 10.1080/00365540410019598

Source DB:  PubMed          Journal:  Scand J Infect Dis        ISSN: 0036-5548


  3 in total

1.  Fulminant legionellosis in two patients treated with infliximab for Crohn's disease: case series and literature review.

Authors:  Adam Hofmann; Yanick Beaulieu; Francis Bernard; Philippe Rico
Journal:  Can J Gastroenterol       Date:  2009-12       Impact factor: 3.522

2.  Neutrophil and Alveolar Macrophage-Mediated Innate Immune Control of Legionella pneumophila Lung Infection via TNF and ROS.

Authors:  Pascal Ziltener; Thomas Reinheckel; Annette Oxenius
Journal:  PLoS Pathog       Date:  2016-04-22       Impact factor: 6.823

Review 3.  Legionnaires' disease: clinical differentiation from typical and other atypical pneumonias.

Authors:  Burke A Cunha
Journal:  Infect Dis Clin North Am       Date:  2010-03       Impact factor: 5.982

  3 in total

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