Literature DB >> 1519724

Light anaesthesia with propofol for paediatric MRI.

M Vangerven1, J Van Hemelrijck, P Wouters, E Vandermeersch, H Van Aken.   

Abstract

Anaesthetic techniques and monitoring equipment may interfere with the technical demands of magnetic resonance imaging. The purpose of this study was to evaluate the safety and efficacy of a light anaesthetic technique with intravenous propofol in nonintubated children. In 20 neuropaediatric patients sedation was induced with propofol 1 mg.kg-1, followed by a continuous infusion titrated to produce adequate immobilisation. Oxygen, 4 l.min-1, was administrated by paediatric face mask. Respiratory rate, end-tidal carbon dioxide tension and oxygen saturation were continuously monitored. In 10 patients capillary blood gas tensions were determined 3 and 20 min after the procedure. Data are reported as mean (SD) and the mean (SD) total propofol dose was 5 (2) mg.kg-1.h-1. Oxygen saturation remained constantly higher than 96% in all patients. End-tidal carbon dioxide tension varied between 35 (7) mmHg 3 min after induction, and 41 (6) mmHg 30 min after the start of the procedure. End-tidal to capillary PCO2 difference was 4 (3) mmHg. Within 20 min after the end of the procedure all patients were fit for dismissal to the ward. One imaging sequence out of 49 was repeated because of movement artefacts. In conclusion, intravenous propofol sedation appears to be a safe and reliable technique for paediatric sedation during magnetic resonance imaging.

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Year:  1992        PMID: 1519724     DOI: 10.1111/j.1365-2044.1992.tb02397.x

Source DB:  PubMed          Journal:  Anaesthesia        ISSN: 0003-2409            Impact factor:   6.955


  8 in total

1.  Low-dose dexmedetomidine as an adjuvant to propofol infusion for children in MRI: A double-cohort study.

Authors:  Makoto Nagoshi; Swayta Reddy; Marisa Bell; Allan Cresencia; Rebecca Margolis; Randall Wetzel; Patrick Ross
Journal:  Paediatr Anaesth       Date:  2018-06-07       Impact factor: 2.556

2.  Hyperintense signal abnormality in subarachnoid spaces and basal cisterns on MR images of children anesthetized with propofol: new fluid-attenuated inversion recovery finding.

Authors:  C G Filippi; A M Ulug; D Lin; L A Heier; R D Zimmerman
Journal:  AJNR Am J Neuroradiol       Date:  2001-02       Impact factor: 3.825

Review 3.  [Total intravenous anesthesia. On the way to standard practice in pediatrics].

Authors:  J M Strauss; J Giest
Journal:  Anaesthesist       Date:  2003-09       Impact factor: 1.041

Review 4.  Propofol. An update of its use in anaesthesia and conscious sedation.

Authors:  H M Bryson; B R Fulton; D Faulds
Journal:  Drugs       Date:  1995-09       Impact factor: 9.546

5.  Procedural sedation analgesia.

Authors:  Saad A Sheta
Journal:  Saudi J Anaesth       Date:  2010-01

6.  Optimal sedative dose of propofol to start MRI in children with cerebral palsy.

Authors:  Eun Jung Kim; Youn Yi Jo; Hae Keum Kil
Journal:  Korean J Anesthesiol       Date:  2011-09-23

7.  A Simulation Study of Propofol Effect-Site Concentration for Appropriate Sedation in Pediatric Patients Undergoing Brain MRI: Pharmacodynamic Analysis.

Authors:  Se Hee Na; Young Song; So Yeon Kim; Hyo Jin Byon; Hwan Ho Jung; Dong Woo Han
Journal:  Yonsei Med J       Date:  2017-11       Impact factor: 2.759

8.  A Novel Propofol Dosing Regimen for Pediatric Sedation during Radiologic Tests.

Authors:  Ji-Young Min; Jeong-Rim Lee; Hye-Mi Lee; Ho-Jae Nam; Hyo-Jin Byon
Journal:  J Clin Med       Date:  2022-08-29       Impact factor: 4.964

  8 in total

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