| Literature DB >> 15196821 |
Deborah J Bidanset1, Rachel J Rybak, Caroll B Hartline, Earl R Kern.
Abstract
For immunocompromised hosts, human cytomegalovirus (CMV) can be a serious problem. For evaluation of antivirals used to treat CMV retinitis, we have used severe combined immunodeficient mice as hosts for human retinal tissue implanted in the eye and subsequently infected with CMV. Treatment with ganciclovir or cidofovir resulted in a significant suppression of CMV replication.Entities:
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Year: 2004 PMID： 15196821 DOI： 10.1016/j.antiviral.2004.02.002
Source DB: PubMed Journal: Antiviral Res ISSN： 0166-3542 Impact factor: 5.970