OBJECTIVE: To investigate the accrual rates and recruitment processes among 3 Midwestern sites during a pilot study on manual therapy for chronic pelvic pain. DESIGN: Multisite pilot study for a randomized, placebo-controlled clinical trial. SETTING:Three chiropractic institutions in or near major metropolitan cities in the Midwestern United States. SUBJECTS:Thirty-nine women aged 18 to 45 with chronic pelvic pain of at least 6 months duration, diagnosed by a board certified gynecologist. MAIN OUTCOME MEASURES: The method of recruitment was collected for each individual who responded to an advertisement and completed an interviewer-administered telephone screen. Participants who were willing and eligible after 3 baseline visits were entered into a randomized clinical trial. The number of responses and accrual rates were determined for the overall study, each of the 3 treatment sites, and each of the 5 recruitment efforts. RESULTS: In this study, 355 women were screened over the telephone and 39 were randomized, making the rate of randomization approximately 10%. The most effective recruitment methods leading to randomization were direct mail (38%) and radio advertisements (34%). However, success of the recruitment process differed by site. CONCLUSIONS: Based on the accrual of this multisite pilot study, a full-scale trial would not be feasible using this study's parameters. However, useful information was gained on recruitment effectiveness, eligibility criteria, and screening protocols among the 3 metropolitan sites.
RCT Entities:
OBJECTIVE: To investigate the accrual rates and recruitment processes among 3 Midwestern sites during a pilot study on manual therapy for chronic pelvic pain. DESIGN: Multisite pilot study for a randomized, placebo-controlled clinical trial. SETTING: Three chiropractic institutions in or near major metropolitan cities in the Midwestern United States. SUBJECTS: Thirty-nine women aged 18 to 45 with chronic pelvic pain of at least 6 months duration, diagnosed by a board certified gynecologist. MAIN OUTCOME MEASURES: The method of recruitment was collected for each individual who responded to an advertisement and completed an interviewer-administered telephone screen. Participants who were willing and eligible after 3 baseline visits were entered into a randomized clinical trial. The number of responses and accrual rates were determined for the overall study, each of the 3 treatment sites, and each of the 5 recruitment efforts. RESULTS: In this study, 355 women were screened over the telephone and 39 were randomized, making the rate of randomization approximately 10%. The most effective recruitment methods leading to randomization were direct mail (38%) and radio advertisements (34%). However, success of the recruitment process differed by site. CONCLUSIONS: Based on the accrual of this multisite pilot study, a full-scale trial would not be feasible using this study's parameters. However, useful information was gained on recruitment effectiveness, eligibility criteria, and screening protocols among the 3 metropolitan sites.
Authors: Kevin Gleason; Donghoon Shin; Michael Rueschman; Tanya Weinstock; Rui Wang; James H Ware; Murray A Mittleman; Susan Redline Journal: Sleep Date: 2014-12-01 Impact factor: 5.849
Authors: Maria A Hondras; Cynthia R Long; Andrea G Haan; Lori Byrd Spencer; William C Meeker Journal: J Altern Complement Med Date: 2008-10 Impact factor: 2.579
Authors: Dale E Rowe; Ronald J Feise; Edward R Crowther; Jaroslaw P Grod; J Michael Menke; Charles H Goldsmith; Michael R Stoline; Thomas A Souza; Brandon Kambach Journal: Chiropr Osteopat Date: 2006-08-21
Authors: Stacie A Salsbury; Elissa Twist; Robert B Wallace; Robert D Vining; Christine M Goertz; Cynthia R Long Journal: Pilot Feasibility Stud Date: 2022-01-14