Literature DB >> 15194629

Use of recombinant factor VIIa to treat life-threatening non-surgical bleeding in a post-partum patient.

G Price1, J Kaplan, G Skowronski.   

Abstract

Ongoing bleeding from patients who have an acquired coagulopathy post-surgery is a common problem. Strategies that are available to combat this problem revolve around the replacement of coagulation factors, platelets, and red blood cells as necessary. These strategies are not always successful and a more direct approach to activating the coagulation system can be more effective and in some instances life saving. We describe the use of recombinant factor VIIa in a patient with ongoing post partum bleeding.

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Year:  2004        PMID: 15194629     DOI: 10.1093/bja/aeh196

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN: 0007-0912            Impact factor:   9.166


  5 in total

1.  Recombinant activated factor VII (rFVIIa/NovoSeven®) in the management of severe postpartum haemorrhage: initial report of a multicentre case series in Japan.

Authors:  Takao Kobayashi; Masao Nakabayashi; Akira Yoshioka; Makoto Maeda; Tsuyomu Ikenoue
Journal:  Int J Hematol       Date:  2011-12-09       Impact factor: 2.490

2.  Recombinant factor VIIa: use in fatal post partum hemorrhage - Indian experience case series and review of literature.

Authors:  Shailesh R Singi; Evita Fernandez; Sunil T Pandya; H R Badrinath
Journal:  Indian J Hematol Blood Transfus       Date:  2009-04-06       Impact factor: 0.900

3.  Recombinant Activated Factor VII (rFVIIa) in the Management of Major Obstetric Haemorrhage: A Case Series and a Proposed Guideline for Use.

Authors:  Charlotte Bomken; Sue Mathai; Tina Biss; Andrew Loughney; John Hanley
Journal:  Obstet Gynecol Int       Date:  2010-02-03

Review 4.  Clinical experiences and current evidence for therapeutic recombinant factor VIIa treatment in nontrauma settings.

Authors:  R Michael Grounds; Charles Bolan
Journal:  Crit Care       Date:  2005-10-07       Impact factor: 9.097

5.  Timely 'off-label' use of recombinant activated factor VII (NovoSeven(®)) can help in avoiding hysterectomy in intractable obstetric bleeding complicated with disseminated intravascular coagulation: A case report and review of the literature.

Authors:  Jyoti Burad; Pradipta Bhakta; Jasvinder Sharma
Journal:  Indian J Anaesth       Date:  2012-01
  5 in total

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