Literature DB >> 15194037

Efficacy of substituting innovator propafenone for its generic formulation in patients with atrial fibrillation.

Guy Amit1, Amit Rosen, Avraham B Wagshal, Dan Y Bonneh, Tzvika Liss, Aviva Grosbard, Reuven Ilia, Amos Katz.   

Abstract

The clinical outcomes of 114 patients with atrial fibrillation who had been treated with the innovator propafenone, and in whom the drug was then replaced with generic propafenone because of cost containment, were compared. The generic formulation was found to be at least as safe and effective as the innovator drug, with regard to atrial fibrillation recurrence, emergency room and hospital admissions, and necessity for concomitant therapy.

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Year:  2004        PMID: 15194037     DOI: 10.1016/j.amjcard.2004.02.071

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN: 0002-9149            Impact factor:   2.778


  7 in total

Review 1.  Cardiovascular disease prevention with a multidrug regimen in the developing world: a cost-effectiveness analysis.

Authors:  Thomas A Gaziano; Lionel H Opie; Milton C Weinstein
Journal:  Lancet       Date:  2006-08-19       Impact factor: 79.321

Review 2.  Clinical equivalence of generic and brand-name drugs used in cardiovascular disease: a systematic review and meta-analysis.

Authors:  Aaron S Kesselheim; Alexander S Misono; Joy L Lee; Margaret R Stedman; M Alan Brookhart; Niteesh K Choudhry; William H Shrank
Journal:  JAMA       Date:  2008-12-03       Impact factor: 56.272

Review 3.  The Impact of Generic Substitution on Health and Economic Outcomes: A Systematic Review.

Authors:  H Gothe; I Schall; K Saverno; M Mitrovic; A Luzak; D Brixner; U Siebert
Journal:  Appl Health Econ Health Policy       Date:  2015-08       Impact factor: 2.561

4.  Knowledge, attitude, and practice of generic medicines among physicians at multispecialty hospital: An observational study.

Authors:  Rajesh B Hadia; Dhaval B Joshi; Kushal H Gohel; Nikhil Khambhati
Journal:  Perspect Clin Res       Date:  2021-05-15

Review 5.  A review of the differences and similarities between generic drugs and their originator counterparts, including economic benefits associated with usage of generic medicines, using Ireland as a case study.

Authors:  Suzanne Dunne; Bill Shannon; Colum Dunne; Walter Cullen
Journal:  BMC Pharmacol Toxicol       Date:  2013-01-05       Impact factor: 2.483

6.  Generic drugs: Review and experiences from South India.

Authors:  Philip Mathew
Journal:  J Family Med Prim Care       Date:  2015 Jul-Sep

7.  Safety and efficacy of generic drugs with respect to brand formulation.

Authors:  Luca Gallelli; Caterina Palleria; Antonio De Vuono; Laura Mumoli; Piero Vasapollo; Brunella Piro; Emilio Russo
Journal:  J Pharmacol Pharmacother       Date:  2013-12
  7 in total

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