| Literature DB >> 15193413 |
Gillis Otten1, Mary Schaefer, Barbara Doe, Hong Liu, Indresh Srivastava, Jan zur Megede, Derek O'Hagan, John Donnelly, Georg Widera, Dietmar Rabussay, Mark G Lewis, Susan Barnett, Jeffrey B Ulmer.
Abstract
The potency of an HIV DNA vaccine was enhanced in rhesus macaques by in vivo electroporation, as judged by increased onset, magnitude and duration of antibody and cell-mediated immune responses against both components of a combination Gag and Env vaccine. These data demonstrate the utility of the electroporation technology for use in large animals.Entities:
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Year: 2004 PMID： 15193413 DOI： 10.1016/j.vaccine.2003.11.073
Source DB: PubMed Journal: Vaccine ISSN： 0264-410X Impact factor: 3.641