BACKGROUND: Post-transplant lymphoproliferative disorder (PTLD) can occur in patients maintained on immunosuppressive therapy following transplantation. This paper describes two cases of PTLD occurring in gingival tissues, in patients receiving ciclosporin following cardiac transplantation. TREATMENT: The lesions were localised to gingival tissues, mimicking ciclosporin-induced gingival overgrowth. They were removed surgically and the ciclosporin dose reduced to help prevent recurrence. CONCLUSION: The importance of histopathological examination of all tissue removed during routine gingivectomy procedures for ciclosporin-induced gingival overgrowth is highlighted.
BACKGROUND: Post-transplant lymphoproliferative disorder (PTLD) can occur in patients maintained on immunosuppressive therapy following transplantation. This paper describes two cases of PTLD occurring in gingival tissues, in patients receiving ciclosporin following cardiac transplantation. TREATMENT: The lesions were localised to gingival tissues, mimicking ciclosporin-induced gingival overgrowth. They were removed surgically and the ciclosporin dose reduced to help prevent recurrence. CONCLUSION: The importance of histopathological examination of all tissue removed during routine gingivectomy procedures for ciclosporin-induced gingival overgrowth is highlighted.
Authors: Jung Hyun Kwon; Joon Chang Song; Sang Hun Lee; So Young Lee; Chul Woo Yang; Yong Soo Kim; Byung Kee Bang Journal: Korean J Intern Med Date: 2005-12 Impact factor: 2.884
Authors: Luis F Gonzalez-Cuyar; Fabio Tavora; Allen P Burke; Christopher D Gocke; Ann Zimrin; John J Sauk; Xiafeng F Zhao Journal: Diagn Pathol Date: 2007-12-19 Impact factor: 2.644