Literature DB >> 15191153

Lidocaine intradermal injection--a new approach in tinnitus therapy: preliminary report.

Marina Savastano1.   

Abstract

The efficacy of lidocaine in controlling tinnitus is well documented. It can be administered intravenously or by transtympanic injection. The first method of delivery can produce cardiovascular and central nervous system adverse reactions. The transtympanic injection can bring about slight sensorineural hearing loss, vertigo, vomiting, and taste disturbances. To improve on results obtained in persons with tinnitus, the vasoactive drug lidocaine was delivered by a novel intradermal route in 68 patients. The control group, which received intradermal saline injection, included 20 patients with tinnitus. As parameters of evaluation, the self-evaluation scale of subjective disturbance and tinnitus loudness were considered. Significant improvement in level of disturbance and tinnitus loudness was observed both in patients with tinnitus intensity less than 10 dB and in those with tinnitus intensity greater than 10 dB. No significant results were observed in the control group. Of particular interest was the complete absence of unpleasant complications with intradermal lidocaine.

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Year:  2004        PMID: 15191153     DOI: 10.1007/bf02850261

Source DB:  PubMed          Journal:  Adv Ther        ISSN: 0741-238X            Impact factor:   3.845


  2 in total

1.  Transcutaneous electrical nerve stimulation (TENS) of upper cervical nerve (C2) for the treatment of somatic tinnitus.

Authors:  Sven Vanneste; Mark Plazier; Paul Van de Heyning; Dirk De Ridder
Journal:  Exp Brain Res       Date:  2010-05-28       Impact factor: 1.972

2.  Oral gabapentin and intradermal injection of lidocaine: is there any role in the treatment of moderate/severe tinnitus?

Authors:  Francesco Ciodaro; Valentina Katia Mannella; Giovanni Cammaroto; Lilla Bonanno; Francesco Galletti; Bruno Galletti
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-09-28       Impact factor: 2.503

  2 in total

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