| Literature DB >> 15187096 |
André Báfica1, Charles A Scanga, Marco Schito, Damien Chaussabel, Alan Sher.
Abstract
Immune activation of HIV gene expression as a consequence of the host response to coinfecting pathogens has been implicated as an important factor in AIDS progression. Immune responsiveness to many of the infectious agents associated with HIV has been demonstrated to depend on a family of innate recognition molecules, known as Toll-like receptors (TLR). Therefore, TLR-pathogen interactions could play an indirect role in regulating HIV-associated disease. In this review, we summarize emerging evidence for the influence of TLR recognition on HIV gene activation and AIDS progression.Entities:
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Year: 2004 PMID: 15187096 DOI: 10.4049/jimmunol.172.12.7229
Source DB: PubMed Journal: J Immunol ISSN: 0022-1767 Impact factor: 5.422