Literature DB >> 1518687

Chest pain in otherwise healthy children and adolescents is frequently caused by exercise-induced asthma.

L Wiens1, R Sabath, L Ewing, R Gowdamarajan, J Portnoy, D Scagliotti.   

Abstract

Chest pain in children and adolescents, unlike in adults, is rarely of cardiac origin and its etiology is frequently unknown. In this age group, chest pain can limit normal activity and sports participation. The reported incidence of exercise-induced asthma in children with chest pain is less than 20%. For this study, 88 otherwise healthy children and adolescents with chest pain followed a treadmill protocol without a warm-up period designed to obtain a target heart rate of 180 or greater during the first several minutes of exercise. Patients maintained this workload for 6 to 8 minutes. Pulmonary function tests performed prior to exercise and at 2, 5, 10, 15, 20, and 25 minutes revealed a decrease in forced expiratory volume in 1 second or peak expiratory flow rate of greater than or equal to 15% in 64 (72.7%) children. Inhaled albuterol resulted in subjective improvement in 97% (35/36) and objective improvement in 70% (25/36) of patients. In otherwise healthy children and adolescents with chest pain, the incidence of exercise-induced asthma seems greater than previously reported. Treatment with bronchodilators may help these patients lead a more active life-style.

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Year:  1992        PMID: 1518687

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  8 in total

Review 1.  Making the diagnosis of asthma in the athlete.

Authors:  Chris Randolph
Journal:  Clin Rev Allergy Immunol       Date:  2005-10       Impact factor: 8.667

Review 2.  Chest pain in children.

Authors:  I C Balfour; P S Rao
Journal:  Indian J Pediatr       Date:  1998 Jan-Feb       Impact factor: 1.967

3.  Chest pain and non-respiratory symptoms in acute asthma.

Authors:  W M Edmondstone
Journal:  Postgrad Med J       Date:  2000-07       Impact factor: 2.401

Review 4.  Chest pain in children.

Authors:  A K Leung; W L Robson; H Cho
Journal:  Can Fam Physician       Date:  1996-06       Impact factor: 3.275

5.  Extracellular cations sensitize and gate capsaicin receptor TRPV1 modulating pain signaling.

Authors:  Gerard P Ahern; Ian M Brooks; Rosa Linda Miyares; Xiang-bin Wang
Journal:  J Neurosci       Date:  2005-05-25       Impact factor: 6.167

Review 6.  Exercise-induced asthma and anaphylaxis.

Authors:  D O Hough; K L Dec
Journal:  Sports Med       Date:  1994-09       Impact factor: 11.136

Review 7.  Exercise-induced bronchospasm in children.

Authors:  Chris Randolph
Journal:  Clin Rev Allergy Immunol       Date:  2008-04       Impact factor: 8.667

8.  Chest pain: characteristics of children/adolescents.

Authors:  Michael J Danduran; Michael G Earing; David C Sheridan; Lauren A Ewalt; Peter C Frommelt
Journal:  Pediatr Cardiol       Date:  2008-02-28       Impact factor: 1.655

  8 in total

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