Literature DB >> 15184222

A randomized controlled trial to change antibiotic prescribing patterns in a community.

Emanuel O Doyne1, Mary Pat Alfaro, Robert M Siegel, Harry D Atherton, Pamela J Schoettker, Jeralyn Bernier, Uma R Kotagal.   

Abstract

BACKGROUND: Excessive and inappropriate use of antibiotics has been identified as a leading cause of the emergence of multiply resistant strains of pneumococci.
OBJECTIVE: To examine the effects of academic detailing and a parental education program on community pediatricians' prescription of antibiotics for young children.
METHODS: Physician leaders in study practices prepared educational modules and presented the modules to their practices. The control groups received only practice-specific report cards. Using a time-series analysis, we collected data on office visits and antibiotic prescriptions filled between May 1, 2000, and April 30, 2001 (baseline period), and between May 1, 2001, and April 30, 2002 (intervention period). Antibiotic prescription rate was defined as the ratio of antibiotic prescriptions filled to the number of office visits.
RESULTS: The antibiotic prescription rate decreased to 0.82 (95% confidence interval, 0.71-0.95) of the baseline rate for the study group (6 practices) and to 0.86 (95% confidence interval, 0.77-0.95) of the baseline for the control group (5 practices). Similar patterns for antibiotic prescription rates were seen for study and control groups both before and after the intervention. Wide variations in prescription rates were observed among the practices, but, in general, the control practices had lower antibiotic prescribing rates during both the baseline and the intervention periods. Use of amoxicillin increased slightly in the study group and decreased slightly in the control group. The use of cephalosporins increased slightly in both groups.
CONCLUSION: Overall, academic detailing appeared to be no more effective in reducing antibiotic use than the practice-specific report cards alone.

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Year:  2004        PMID: 15184222     DOI: 10.1001/archpedi.158.6.577

Source DB:  PubMed          Journal:  Arch Pediatr Adolesc Med        ISSN: 1072-4710


  14 in total

Review 1.  Local opinion leaders: effects on professional practice and health care outcomes.

Authors:  Gerd Flodgren; Elena Parmelli; Gaby Doumit; Melina Gattellari; Mary Ann O'Brien; Jeremy Grimshaw; Martin P Eccles
Journal:  Cochrane Database Syst Rev       Date:  2011-08-10

Review 2.  Reducing antibiotic prescribing for children with respiratory tract infections in primary care: a systematic review.

Authors:  Talley A Vodicka; Matthew Thompson; Patricia Lucas; Carl Heneghan; Peter S Blair; David I Buckley; Niamh Redmond; Alastair D Hay
Journal:  Br J Gen Pract       Date:  2013-07       Impact factor: 5.386

3.  Clinical vignettes provide an understanding of antibiotic prescribing practices in neonatal intensive care units.

Authors:  Sameer Patel; Timothy Landers; Elaine Larson; Theoklis Zaoutis; Patricia Delamora; David A Paul; Jennifer Wong-McLoughlin; Yu-Hui Ferng; Lisa Saiman
Journal:  Infect Control Hosp Epidemiol       Date:  2011-06       Impact factor: 3.254

Review 4.  Interventions to improve antibiotic prescribing practices in ambulatory care.

Authors:  S R Arnold; S E Straus
Journal:  Cochrane Database Syst Rev       Date:  2005-10-19

Review 5.  Continuing education meetings and workshops: effects on professional practice and healthcare outcomes.

Authors:  Louise Forsetlund; Mary Ann O'Brien; Lisa Forsén; Liv Merete Reinar; Mbah P Okwen; Tanya Horsley; Christopher J Rose
Journal:  Cochrane Database Syst Rev       Date:  2021-09-15

Review 6.  Continuing education meetings and workshops: effects on professional practice and health care outcomes.

Authors:  Louise Forsetlund; Arild Bjørndal; Arash Rashidian; Gro Jamtvedt; Mary Ann O'Brien; Fredric Wolf; Dave Davis; Jan Odgaard-Jensen; Andrew D Oxman
Journal:  Cochrane Database Syst Rev       Date:  2009-04-15

7.  Limited efficacy of a nonrestricted intervention on antimicrobial prescription of commonly used antibiotics in the hospital setting: results of a randomized controlled trial.

Authors:  M Masiá; C Matoses; S Padilla; A Murcia; V Sánchez; I Romero; A Navarro; I Hernández; F Gutiérrez
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2008-03-04       Impact factor: 3.267

8.  Impact of statewide program to promote appropriate antimicrobial drug use.

Authors:  Edward A Belongia; Mary Jo Knobloch; Burney A Kieke; Jeffrey P Davis; Carolyn Janette; Richard E Besser
Journal:  Emerg Infect Dis       Date:  2005-06       Impact factor: 6.883

9.  Local opinion leaders: effects on professional practice and healthcare outcomes.

Authors:  Gerd Flodgren; Mary Ann O'Brien; Elena Parmelli; Jeremy M Grimshaw
Journal:  Cochrane Database Syst Rev       Date:  2019-06-24

10.  Significant reduction of antibiotic use in the community after a nationwide campaign in France, 2002-2007.

Authors:  Elifsu Sabuncu; Julie David; Claire Bernède-Bauduin; Sophie Pépin; Michel Leroy; Pierre-Yves Boëlle; Laurence Watier; Didier Guillemot
Journal:  PLoS Med       Date:  2009-06-02       Impact factor: 11.069

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