Literature DB >> 15184189

Enhancement of Cry19Aa mosquitocidal activity against Aedes aegypti by mutations in the putative loop regions of domain II.

Mohd Amir F Abdullah1, Donald H Dean.   

Abstract

Improvements in the mosquitocidal activity of Bacillus thuringiensis Cry19Aa were achieved by protein engineering of putative surface loop residues in domain II through rational design. The improvement of Aedes toxicity in Cry19Aa was 42,000-fold and did not affect its toxicity against Anopheles or Culex.

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Year:  2004        PMID： 15184189      PMCID： PMC427746          DOI： 10.1128/AEM.70.6.3769-3771.2004

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN： 0099-2240            Impact factor:   4.792


  10 in total

1.  SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling.

Authors:  N Guex; M C Peitsch
Journal:  Electrophoresis       Date:  1997-12       Impact factor: 3.535

2.  ProMod and Swiss-Model: Internet-based tools for automated comparative protein modelling.

Authors:  M C Peitsch
Journal:  Biochem Soc Trans       Date:  1996-02       Impact factor: 5.407

Review 3.  Probing the mechanism of action of Bacillus thuringiensis insecticidal proteins by site-directed mutagenesis--a minireview.

Authors:  D H Dean; F Rajamohan; M K Lee; S J Wu; X J Chen; E Alcantara; S R Hussain
Journal:  Gene       Date:  1996-11-07       Impact factor: 3.688

4.  Characterization of six highly mosquitocidal Bacillus thuringiensis strains that do not belong to H-14 serotype.

Authors:  A Ragni; I Thiéry; A Delécluse
Journal:  Curr Microbiol       Date:  1996-01       Impact factor: 2.188

5.  Enhanced toxicity of Bacillus thuringiensis Cry3A delta-endotoxin in coleopterans by mutagenesis in a receptor binding loop.

Authors:  S J Wu; C N Koller; D L Miller; L S Bauer; D H Dean
Journal:  FEBS Lett       Date:  2000-05-12       Impact factor: 4.124

6.  Lack of cross-resistance to Cry19A from Bacillus thuringiensis subsp. jegathesan in Culex quinquefasciatus (Diptera: Culicidae) resistant to cry toxins from Bacillus thuringiensis subsp. israelensis.

Authors:  M C Wirth; A Delécluse; W E Walton
Journal:  Appl Environ Microbiol       Date:  2001-04       Impact factor: 4.792

Review 7.  Bacillus thuringiensis and its pesticidal crystal proteins.

Authors:  E Schnepf; N Crickmore; J Van Rie; D Lereclus; J Baum; J Feitelson; D R Zeigler; D H Dean
Journal:  Microbiol Mol Biol Rev       Date:  1998-09       Impact factor: 11.056

8.  Contribution of the 65-kilodalton protein encoded by the cloned gene cry19A to the mosquitocidal activity of Bacillus thuringiensis subsp. jegathesan.

Authors:  M L Rosso; A Delécluse
Journal:  Appl Environ Microbiol       Date:  1997-11       Impact factor: 4.792

9.  Identification of amino acid residues of Bacillus thuringiensis delta-endotoxin CryIAa associated with membrane binding and toxicity to Bombyx mori.

Authors:  H Lu; F Rajamohan; D H Dean
Journal:  J Bacteriol       Date:  1994-09       Impact factor: 3.490

10.  Introduction of Culex toxicity into Bacillus thuringiensis Cry4Ba by protein engineering.

Authors:  Mohd Amir F Abdullah; Oscar Alzate; Marwan Mohammad; Rebecca J McNall; Michael J Adang; Donald H Dean
Journal:  Appl Environ Microbiol       Date:  2003-09       Impact factor: 4.792
  10 in total
  9 in total

1.  Investigating the properties of Bacillus thuringiensis Cry proteins with novel loop replacements created using combinatorial molecular biology.

Authors:  Craig R Pigott; Martin S King; David J Ellar
Journal:  Appl Environ Microbiol       Date:  2008-04-11       Impact factor: 4.792

2.  Alanine scanning analyses of the three major loops in domain II of Bacillus thuringiensis mosquitocidal toxin Cry4Aa.

Authors:  Mohammad Tofazzal Hossain Howlader; Yasuhiro Kagawa; Ai Miyakawa; Ayaka Yamamoto; Tetsuya Taniguchi; Tohru Hayakawa; Hiroshi Sakai
Journal:  Appl Environ Microbiol       Date:  2009-11-30       Impact factor: 4.792

3.  Mutagenic analysis of putative domain II and surface residues in mosquitocidal Bacillus thuringiensis Cry19Aa toxin.

Authors:  Jong Yul Roh; Manoj S Nair; Xinyan Sylvia Liu; Donald H Dean
Journal:  FEMS Microbiol Lett       Date:  2009-04-27       Impact factor: 2.742

Review 4.  Bt toxin modification for enhanced efficacy.

Authors:  Benjamin R Deist; Michael A Rausch; Maria Teresa Fernandez-Luna; Michael J Adang; Bryony C Bonning
Journal:  Toxins (Basel)       Date:  2014-10-22       Impact factor: 4.546

Review 5.  In silico models for predicting vector control chemicals targeting Aedes aegypti.

Authors:  J Devillers; C Lagneau; A Lattes; J C Garrigues; M M Clémenté; A Yébakima
Journal:  SAR QSAR Environ Res       Date:  2014-10-02       Impact factor: 3.000

6.  Using phage display technology to obtain Crybodies active against non-target insects.

Authors:  Tania Domínguez-Flores; María Dolores Romero-Bosquet; Diana Marcela Gantiva-Díaz; María José Luque-Navas; Colin Berry; Antonio Osuna; Susana Vílchez
Journal:  Sci Rep       Date:  2017-11-02       Impact factor: 4.379

Review 7.  Making 3D-Cry Toxin Mutants: Much More Than a Tool of Understanding Toxins Mechanism of Action.

Authors:  Susana Vílchez
Journal:  Toxins (Basel)       Date:  2020-09-16       Impact factor: 4.546

Review 8.  Can (We Make) Bacillus thuringiensis Crystallize More Than Its Toxins?

Authors:  Guillaume Tetreau; Elena A Andreeva; Anne-Sophie Banneville; Elke De Zitter; Jacques-Philippe Colletier
Journal:  Toxins (Basel)       Date:  2021-06-26       Impact factor: 4.546

Review 9.  Genetic Modification Approaches for Parasporins Bacillus thuringiensis Proteins with Anticancer Activity.

Authors:  Miguel O Suárez-Barrera; Lydia Visser; Paola Rondón-Villarreal; Diego F Herrera-Pineda; Juan S Alarcón-Aldana; Anke Van den Berg; Jahir Orozco; Efraín H Pinzón-Reyes; Ernesto Moreno; Nohora J Rueda-Forero
Journal:  Molecules       Date:  2021-12-10       Impact factor: 4.411
  9 in total

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