Literature DB >> 15182912

Cannabis improves night vision: a case study of dark adaptometry and scotopic sensitivity in kif smokers of the Rif mountains of northern Morocco.

E B Russo1, A Merzouki, J Molero Mesa, K A Frey, P J Bach.   

Abstract

Previous reports have documented an improvement in night vision among Jamaican fishermen after ingestion of a crude tincture of herbal cannabis, while two members of this group noted that Moroccan fishermen and mountain dwellers observe an analogous improvement after smoking kif, sifted Cannabis sativa mixed with tobacco (Nicotiana rustica). Field-testing of night vision has become possible with a portable device, the LKC Technologies Scotopic Sensitivity Tester-1 (SST-1). This study examines the results of double-blinded graduated THC administration 0-20 mg (as Marinol) versus placebo in one subject on measures of dark adaptometry and scotopic sensitivity. Analogous field studies were performed in Morocco with the SST-1 in three subjects before and after smoking kif. In both test situations, improvements in night vision measures were noted after THC or cannabis. It is believed that this effect is dose-dependent and cannabinoid-mediated at the retinal level. Further testing may assess possible clinical application of these results in retinitis pigmentosa or other conditions.

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Year:  2004        PMID: 15182912     DOI: 10.1016/j.jep.2004.03.029

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN: 0378-8741            Impact factor:   4.360


  11 in total

1.  Endocannabinoid CB1 receptors modulate visual output from the thalamus.

Authors:  Miguel A Dasilva; Kenneth L Grieve; Javier Cudeiro; Casto Rivadulla
Journal:  Psychopharmacology (Berl)       Date:  2011-07-20       Impact factor: 4.530

2.  Contrast sensitivity and motion discrimination in cannabis users.

Authors:  Elena Mikulskaya; Frances Heritage Martin
Journal:  Psychopharmacology (Berl)       Date:  2018-06-16       Impact factor: 4.530

Review 3.  Endocannabinoids in the retina: from marijuana to neuroprotection.

Authors:  Stephen Yazulla
Journal:  Prog Retin Eye Res       Date:  2008-08-03       Impact factor: 21.198

Review 4.  Cannabinoids Regulate Sensory Processing in Early Olfactory and Visual Neural Circuits.

Authors:  Thomas Heinbockel; Alex Straiker
Journal:  Front Neural Circuits       Date:  2021-07-07       Impact factor: 3.492

Review 5.  TRPV1 and Endocannabinoids: Emerging Molecular Signals that Modulate Mammalian Vision.

Authors:  Daniel A Ryskamp; Sarah Redmon; Andrew O Jo; David Križaj
Journal:  Cells       Date:  2014-09-12       Impact factor: 6.600

6.  Cannabinoids Modulate Light Signaling in ON-Sustained Retinal Ganglion Cells of the Mouse.

Authors:  Terence Peter Middleton; Jin Yu Huang; Dario Alejandro Protti
Journal:  Front Neural Circuits       Date:  2019-05-21       Impact factor: 3.492

7.  Cannabinoid Receptors CB1 and CB2 Modulate the Electroretinographic Waves in Vervet Monkeys.

Authors:  Joseph Bouskila; Vanessa Harrar; Pasha Javadi; Amy Beierschmitt; Roberta Palmour; Christian Casanova; Jean-François Bouchard; Maurice Ptito
Journal:  Neural Plast       Date:  2016-03-16       Impact factor: 3.599

Review 8.  Expression and Function of the Endocannabinoid System in the Retina and the Visual Brain.

Authors:  Jean-François Bouchard; Christian Casanova; Bruno Cécyre; William John Redmond
Journal:  Neural Plast       Date:  2015-12-29       Impact factor: 3.599

9.  Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells.

Authors:  Loïs S Miraucourt; Jennifer Tsui; Delphine Gobert; Jean-François Desjardins; Anne Schohl; Mari Sild; Perry Spratt; Annie Castonguay; Yves De Koninck; Nicholas Marsh-Armstrong; Paul W Wiseman; Edward S Ruthazer
Journal:  Elife       Date:  2016-08-08       Impact factor: 8.140

10.  Cannabinoids affect the mouse visual acuity via the cannabinoid receptor type 2.

Authors:  Bruno Cécyre; Ismaël Bachand; François Papineau; Chloé Brochu; Christian Casanova; Jean-François Bouchard
Journal:  Sci Rep       Date:  2020-09-25       Impact factor: 4.379

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